Published in Vaccine Weekly, January 19th, 2005
This finding could help scientists develop a vaccine that is significantly more effective at protecting children against the disease.
The St. Jude researchers determined the shape of a large, paddle-like molecule that Streptococcus pneumoniae bacteria use to latch onto cells lining the throat and lungs. The protein, called CbpA, binds to a molecule on the cell called pIgR, which takes antibodies from the bloodstream on one side of the cell and transports them to the...
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