Stem Cell Research

Fetal, cord blood, and adult lymphocyte progenitors generate similar B cells

Published in Vaccine Weekly, January 19th, 2005

Human fetal, cord blood, and adult lymphocyte progenitors have similar potential for generating B cells with a diverse immunoglobulin repertoire.

According to a study from the United States, "Several characteristics of the immunoglobulin (lg) repertoire in fetuses and adults set them apart from each other. Functionally, this translates into differences in the affinity and effectiveness of the humoral immune response between adults and the very young. At least 2 possibilities could explain these differences: fetal and adult lymphocyte progenitors differ significantly in their potential to form a diverse repertoire, and factors extrinsic to the immunoglobulin locus are...

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Source: Vaccine Weekly (2005-01-19)

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