Clinical Trials
Race may influence the response to recombinant HIV-1 gp120 vaccines
Published in Vaccine Weekly, January 26th, 2005
"We compared neutralizing antibody responses in human immunodeficiency virus (HIV) type 1 gp120 vaccine recipients by age, sex, and race. Four phase 1 or 2 trials involving 505 vaccinated subjects were analyzed. Age and sex had no detectable effect on neutralizing antibody responses," scientists in the United States report.
"However, race influenced the response to one vaccine, MN gp120, in alum. Four inoculations with this vaccine generated higher serum titers of neutralizing antibodies in African Americans than in whites. Despite potent neutralization of T cell line adapted HIV-1,...
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Source: Vaccine Weekly (2005-01-26)
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