Vaccine Adjuvant

Challenges facing adjuvants for cancer immunotherapy reviewed

Published in Vaccine Weekly, February 2nd, 2005

Researchers review the challenges facing adjuvants for cancer immunotherapy in a recent issue of Immunology and Cell Biology.

According to a study from Cuba, "An adjuvant is defined as a product that increases or modulates the immune response against an antigen. Based on this general definition many authors have postulated that the ideal adjuvant should increase the potency of the immune response, while being non-toxic and safe. Although dozens of different adjuvants have been shown to be effective in preclinical and clinical studies, only aluminum-based salts (Alum) and squalene-oil-water emulsion (MF59) have been approved for human use. However, for the...

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Source: Vaccine Weekly (2005-02-02)

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