Published in Vaccine Weekly, February 2nd, 2005
"The application of the baculovirus-insect cell expression system for the production of integral membrane and secreted proteins is often more troublesome than for cytoplasmic proteins. One protein expressed at low levels in insect cells is the Theileria parva sporozoite surface protein p67. Theileria parva is a protozoan parasite, which causes the tick-transmitted disease East Coast fever in cattle," investigators in the Netherlands report.
"Baculovirus vectors were engineered to produce a secreted form of p67...
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