Malaria Vaccines

Recent findings illuminate research in malaria vaccines

Published in Vaccine Weekly, February 2nd, 2005

Investigators in France and the United States have published new malaria vaccines data.

Study 1: Researchers have completed a preliminary structural analysis of the ectoplasmic region of apical membrane antigen 1 from Plasmodium vivax, a malaria-vaccine candidate.

"Apical membrane antigen 1 (AMA1), a type 1 transmembrane protein present in the microneme organelles of Plasmodium, is a leading malaria-vaccine candidate. The ectoplasmic region of AMA1 from P. vivax has been expressed in Pichia pastoris and crystallized in two different forms: an orthorhombic form (space group P2₁ 2₁ 2₁ ,...

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Source: Vaccine Weekly (2005-02-02)

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