Salmonella Vaccines
Recent findings in salmonella vaccines described
Published in Vaccine Weekly, February 16th, 2005
Study 1: An attenuated Salmonella live vaccine expressing OprF-OprI from Pseudomonas aeruginosa exhibited enhanced immunogenicity in the murine airway mucosa.
"We constructed an oral live vaccine based on the attenuated aroA mutant Salmonella enterica serovar Typhimurium strain SL3261 expressing outer membrane proteins F and I (OprF-Oprl) from Pseudomonas aeruginosa and investigated it in a mouse model. Strains with in vivo inducible protein expression with the P-pacC promoter showed good infection rates and immunogenicity but...
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Source: Vaccine Weekly (2005-02-16)
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