Published in Vaccine Weekly, February 16th, 2005
"HIV variation presents an obstacle to a global AIDS vaccine. Viral diversity and host variations in MHC expression both affect vaccine responses. Whether CD8 T cells from HIV-infected donors in 1 part of the world cross-recognize isolates from other regions will provide guidance about whether country-specific vaccines are needed. We compared recognition of HIVIIIB and representative B' (Thai B) and recombinant C/B' virus strains endemic in...
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