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Leishmaniasis Vaccine

Dendritic cells in Leishmania infection reviewed

Published in Vaccine Weekly, March 16th, 2005

Researchers review dendritic cells in Leishmania infection in a recent issue of Microbes and Infection.

According to a study from Italy, "Dendritic cells (DCs) are key elements of the immune system, which function as sentinel in the periphery and alert T lymphocytes about the type of invading antigen and address their polarization, in order to mount an efficacious immune response. Leishmania species are parasitic protozoa which may cause severe disease in humans and domestic animals."

"In this work, the main studies concerning the role of DCs in Leishmania infection are reviewed, in both the murine and human models," said...

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