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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . March 23rd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Atherosclerosis Vaccine - Immunomodulation of atherosclerosis reviewed

HIV/AIDS Vaccine - Antibodies to HIV vif turns HIV infection into benign problem

Human Papillomavirus Vaccine - Human papillomavirus oncoprotein vaccine eradicates established tumors

Influenza Vaccine - Immunostimulant patch improves response to influenza vaccine in elderly

Measles Vaccine - Measles genotype in Spain after measles elimination plan reported

Adverse Drug Reaction - U.S. FDA approves i.v. immune globulin for adverse reactions to smallpox vaccine

Allergy and Immunology - Costimulatory cytokines rescue CD8+ T cell response to peptide immunization

Alzheimer Disease - A-beta immunization protects against cognitive impairment

Alzheimer Disease - A-beta vaccination affects plaque pathology in absence of encephalitis

Alzheimer Disease - Diagnoses of Alzheimer disease expected to increase

Assisted Reproduction - Sperm washing techniques are safe, may address fertility needs of HIV+ men

Cancer Vaccines - Researchers' data advance cancer vaccines research

Avian Influenza - Maine officials prepare for possibility of avian flu

Avian Influenza - U.S. prepares to test bird flu vaccines

Avian Influenza - Vietnam confirms fourth case of bird flu in a week

Bacteriology - Autophagy provides new vaccine approach

Bovine Herpesvirus - Bovine herpesvirus gene promotes virus growth and reactivation

Breast Cancer - HER2 DNA delivered by adenoviral vector

Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge

Breast Cancer Vaccine - Anti-HER2 antibodies block HER2 phosphorylation and signaling

Breast Cancer Vaccine - Killed Mycobacterium vaccae may augment efficacy of trastuzumab

Business & Finance - Anti-infectives focused company gets NASDAQ extension on listing requirements

Business Update - Biopharma company signs agreement with Celliance BioServices, Inc.

Business Update - Sentigen Holding Corp. Announces the Sale of Its Specialty Media Division

Cancer Therapy - Study shows patients get more benefit than thought from early cancer treatment

Malaria Vaccines - Studies advance knowledge in malaria vaccines research

Cancer Vaccines - Amino acid substitution improves enzymatic stability of MUC2 epitope

Cancer Vaccines - B-lymphocytes activated by CD40 ligand induce anti-tumor response

Cancer Vaccines - Distinct overlapping T helper epitopes found in 37-58 region of SSX-2

Cancer Vaccines - Findings describe new data in cancer vaccines research

Cancer Vaccines - IL-12-secreting dendritic cells generate anti-tumor immunity in mice

Cancer Vaccines - Immunotherapy for malignant gliomas reviewed

Cancer Vaccines - Multi-epitope vaccines elicit CD8+ cytotoxic T cells

Cancer Vaccines - PLGA microspheres improve antigen delivery to dendritic cells

Cancer Vaccines - TP-3 immunotoxins improve antitumor activity in mice with osteosarcoma

Cervical Cancer - Collaboration will focus on topical anti-HPV treatment

Cholera - Study finds cholera vaccine effective

Clinical Trials - Drug company to focus on developing cancer and infectious diseases products

Colon Cancer - Duke develops new breed of viral vaccines to battle colon cancer

Contraception - Chicken riboflavin carrier protein has immunocontraceptive potential

Coronavirus - Recurrent feline coronavirus infection and role of cellular immunity reported

Cytomegalovirus Vaccine - Codominant T cell epitopes of human cytomegalovirus explored

Cytomegalovirus Vaccine - Cytomegalovirus glycoprotein H induces mucosal and systemic immunity

Cytomegalovirus Vaccine - Methods to enumerate antigen-specific T-cell responses compared

DNA Vaccine - Bacterial DNA-specific modified base triggers cytokine production in mice

DNA Vaccine - DNA-loaded biodegradable microparticles useful for vaccine delivery systems

Dental Caries - Microparticles promote immunogenicity of Streptococcus peptide

Diabetes Therapy - Research in diabetes therapy provides new insights

Disease Transmission - Risk of HSV-1 infection rises with oral sex

Domestic Violence - Women in abusive relationships with HIV+ men are at risk of infection

Emerging Disease -  Plesiomonas shigelloides is emerging pathogen with unusual features

Finance - Developer, manufacturer of human cell lines reports 2004 results

Finance - Diagnostics product company announces 2004 financial results

Finance - Pharma company releases financial results showing increase in net income

Finance - Pharmaceutical company reports fourth quarter and full year 2004 results

Finance - Vaccine maker identifies post-close adjustments to 2004 financial results

Finance - Vaccine-focused biopharmaceutical company announces FY 2004 financial results

Gonorrhea - Genetic typing of porin protein of Neisseria gonorrhoeae reported

HIV/AIDS Prevention - Preliminary safety data from phase 1 HIV vaccine trial reported

HIV/AIDS Vaccine - Anti-HIV antibodies require few residues to neutralize HIV-1

HIV/AIDS Vaccine - Antibody response elicited by trimeric HIV glycoproteins analyzed

HIV/AIDS Vaccine - Clinical evaluation of HIV/AIDS vaccine initiatied

HIV/AIDS Vaccine - Differential immune containment of HIV-1 clade B strains found

HIV/AIDS Vaccine - Expression of gag protein of HIV-1CN in Pichia pastoris reported

HIV/AIDS Vaccine - HIV-1 virus-like particles are potent immune stimulators

HIV/AIDS Vaccine - Inactivated HIV antigen plus CpG ODN protects against infection

HIV/AIDS Vaccine - Inducing murin CCR5-downregulating antibodies prevents HIV infection

HIV/AIDS Vaccine - Macaque MHC molecules presenting immunodominant SIV epitopes analyzed

HIV/AIDS Vaccine - Modified HIV envelope proteins exhibit enhanced binding to antibodies

Haemophilus Vaccines - Studies describe new findings in haemophilus vaccines research

Helicobacter Vaccines - New findings in helicobacter vaccines described

Hematology - Immature dendritic cells help CD40 ligand regress established myeloma

Hepatitis C Virus Vaccine - Interferon augments immune response to DNA vaccine against HCV core antigen

Herpesvirus Vaccine - Cutaneous antigen expression by herpes-specific lymphocytes explored

Herpesvirus Vaccine - Ocular delivery of herpes epitopes induces local and systemic responses

Immunology - Autologous IgG with the inflammation-associated marker is immunogenic

Immunology - Studies add new findings to immunology body of knowledge

Infant Mortality - Combining interventions into packages could save more lives cost effectively

Infectious Bursal Disease - Enhanced virulence of infectious bursal disease determined by B-segment

Infectious Laryngotracheitis Virus - Relevance of infectious laryngotracheitis virus gJ proteins reviewed

Influenza - Infectious disease organization comments on influenza immunization studies

Influenza - Vaccination programs for children in U.S., Canada based on little evidence

Influenza Vaccine - Britain stockpiles drugs to combat flu

Influenza Vaccine - British regulators say Chiron free to resume making flu vaccine

Influenza Vaccine - Guide for flu and pneumococcal vaccines in cancer patients released

Influenza Vaccine - Medical practice expenses from influenza vaccinations estimated

Influenza Vaccine - Norway to be supplied with special vaccines in event of influenza pandemic

Legal Issues - Appellate court revives claim that vaccine disabled boy

Malaria Vaccine - Baculovirus-based malaria vaccine shows promise in Senegalese village

Malaria Vaccine - Epitope mapping of malaria parasite inhibitory antibodies reported

Malaria Vaccine - Modified HRP-I peptide analogue protects against malaria

Malaria Vaccines - Reports add new data to malaria vaccines research

Melanoma Vaccine - MAGE-A3 is a frequent tumor antigen of metastasized melanoma

Melanoma Vaccine - Peptide vaccine has minimal benefit in patients with stage IV melanoma

Melanoma Vaccine - Vaccine induces T cell response against tumor antigen survivin

Melanoma Vaccines - Findings advance knowledge in melanoma vaccines research

Meningitis Vaccine -  Neisseria meningitidis proteins reduce bacteremia in infant rats

Meningitis Vaccine -  Neisseria NadA promotes bacterial penetration into epithelial cells

Mucosal Immunization - Reports describe recent advances in mucosal immunization research

Myeloma - "Smart" immune cells kill more cancer

Natural Products - Bronchitis symptoms reduced by substance in S. African geranium, study shows

Nosocomial Infections - U.S.FDA grants priorty status to drug for serious skin, soft tissue infections

Periodontal Disease -  Porphyromonas gingivalis protein antisera causes phagocytosis

Personnel - Christopher S. Henney invited to join board of cancer management company

Philanthropy - U.N. health body welcomes Canadian gift

Pneumococcal Vaccine -  Streptococcus iron-uptake lipoproteins elicit antibody responses

Pneumococcal Vaccine - Complement loss affects antibody responses to pneumococcal antigen

Pneumococcal Vaccine - Molecular epidemiology of pneumococcal colonization investigated

Pneumococcal Vaccine - Rapid multiplex assay for serotyping pneumococci developed

Polio Vaccine - Spread of vaccine-derived poliovirus from a paralytic case reported

Prostate Cancer - Immune-based therapies for prostate cancer reviewed

Prostate Cancer - Pharmaceutical company announces results of prostate cancer clinical trial

Prostate Cancer - Provenge/Avastin combo increases PSADT

Prostate Cancer Vaccines - Researchers' findings advance prostate cancer vaccines research

Rabies Vaccine - New rabies vaccine manufactured in India is safe and immunogenic

Respiratory Syncytial Virus - Intranasal siRNA nanoparticles inhibit respiratory syncytial virus

SARS Vaccine - Binding system restores interaction between SARS protein and receptor

SARS Vaccine - Intranasal immunization with inactivated SARS-CoV induces antibodies

SARS Vaccines - Recent findings illuminate research in SARS vaccines

Salmonella Vaccine - Absence of substance P receptor enhances IgA response

Salmonella Vaccine - Regulation of cytokine Salmonella-induced mRNA expression examined

Salmonella Vaccine - Type 1 fimbriae protects laying hens against Salmonella

Sepsis - Immunogenicity of brominated protein reported

Shigellosis Vaccine -  Shigella flexneri vaccine strains characterized

Shigellosis Vaccine -  Shigella porin induces expression of IgM, IgG2a, and IgA

Smallpox - Imvamune vaccination expected to be effective against smallpox after 3 days

Smallpox Vaccine - Smallpox vaccine does not protect macaques with AIDS from monkeypox

Smallpox Vaccine - WHO seeking to expand world stockpile of smallpox vaccines

Staphylococcus Vaccine - Mutant staphylococcal enterotoxin protects against infection

Toxoplasmosis Vaccine -  Toxoplasma gondii proteins protect against oral infection

Tuberculosis Vaccines - Cutaneous tuberculosis evoked by BGG vaccination in healthy baby

Tuberculosis Vaccines - Findings in tuberculosis vaccines provide new insights

Urinary Tract Infection - Dr fimbriae reduces E. coli urinary tract infection mortality

Vaccine Adjuvant - Structure-activity relations of water-in-oil vaccines investigated

Vaccine Delivery - Biodegradable microparticles developed for vaccine antigen delivery

Vaccine Delivery - Fusogenic liposome used as vaccine carrier to induce CTL response

Vaccine Development - Biopharma initiates new Botulinum toxin therapeutic program

Vaccine Development - Clinical-stage pharma reports on anticancer progress at angiogenesis symposium

Vaccine Development - Formulation of polymeric microspheres for antigen delivery examined

Vaccine Development - Sugar epitopes are potential disease transmission blocking targets

Vaccine Development - Toll-like receptors induce antigen cross-presentation

Vaccine Development - Virus-like particles as carriers for T-cell epitopes investigated

Vaccinia Virus - Vaccinia virus protein functions at mitochondria to inhibit apoptosis

Virology - Studies add new findings to virology body of knowledge

Virology Vaccine - Nasally administered siRNA inhibits respiratory viruses

Virology Vaccine - Viral DNA-binding domain elicits anti-DNA antibodies

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