Malaria Vaccine
Baculovirus-based malaria vaccine shows promise in Senegalese village
Published in Vaccine Weekly, March 23rd, 2005
"Antibodies to Plasmodium falciparum C-terminal merozoite surface protein 1 (PfMSP-1p19) have been correlated with protection against malaria, but this association may apply to many merozoite antigens. To address this question, we conducted a prospective serological study of 205 individuals in an active 5-month clinical survey in a Senegalese village where malaria is mesoendemic. Before the 2000 rainy season, antibody responses specific for recombinant baculovirus PfMSP-1p19 or merozoite extracts were compared with two in vitro functional antibody activities (inhibition of...
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Source: Vaccine Weekly (2005-03-23)
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