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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . March 30th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Anthrax Vaccine - Mucosal administration of rPA protects against inhalational anthrax

Cancer Vaccines - Human tumor antigens recognized by T cells listed

Malaria Vaccine - Allele specificity of antibody responses against P. falciparum outlined

Pneumococcal Vaccine - Pneumococcal polysaccharide mimotope induces protective response

Polio Vaccine - Immunization schedules affect excretion of polio vaccine strains

Anthrax Vaccine - HEPA/vaccine plan for indoor anthrax remediation outlined

Avian Influenza - Grandfather of two bird flu patients in Vietnam also infected with the virus

Avian Influenza - Nurse contracts bird flu in Vietnam; source of virus is unclear

Avian Influenza - Vietnam reports second case of bird flu with no symptoms

Bacterial Meningitis - New vaccine for bacterial meningitis

Business & Finance - Anti-infectives-focused biotech company reports Q4, year end 2004 results

Cancer Vaccines - Researchers' findings advance cancer vaccines research

Cancer Immunotherapy - Lymphocyte contamination makes genetically altered dendritic cells disappear

Cancer Therapy - Alliance established for trial of non-small cell lung cancer vaccine

Cancer Therapy - Vaccine adjuvant shows enhanced immune response in prostate cancer patients

Cancer Vaccines - Branched lysine peptide has antitumor effect in rat glioma model

Cancer Vaccines - Dendritic cell vaccine elicits long-lasting protective tumor immunity

Immunology - Researchers' findings advance immunology research

Cancer Vaccines - Dendritic cells have limited potential in immunotherapy

Cancer Vaccines - Dendritic cells modulate antitumor responses

Cancer Vaccines - HLA-DR beta1*0101- and 1*0401-restricted epitopes identified

Cancer Vaccines - Highly specific overexpression of SOX11 occurs in malignant gliomas

Cancer Vaccines - New findings in cancer vaccines described

Cancer Vaccines - Peptide with native disulfide bonds enhances antitumor activity

Pneumococcal Vaccines - Studies add new findings to pneumococcal vaccines body of knowledge

Cancer Vaccines - Peptides from taxol resistance-related protein elicit T-cell responses

Cancer Vaccines - Virosomes for antigen and DNA delivery reviewed

Childhood Immunization - Many children are undervaccinated in their first 2 years of life

Childhood Immunization - Openness is key to winning the war over MMR

Chlamydia Vaccine - Vaccine candidates against Chlamydia pneumoniae identified

Collaborations - Companies enter collaboration to develop therapeutic hepatitis B vaccine

Cysticercosis Vaccine - Method for monitoring vaccines against cysticercosis developed

DPT Vaccine - Diphtheria/pertussis vaccine components should be inactivated toxins

DPT Vaccine - Pertussis toxoid reduces immunogenicity of diphtheria and tetanus

Diabetes Genomics and Genetics - Adenovirus transgenes expressed in beta cells prevent type 1 diabetes

Drug Development - Further investment made in smallpox vaccine production

Drug Resistance - Drug resistance in Streptococcus pneumoniae isolates reported

Ebola Virus - Ebola glycoprotein toxicity mediated by dynamin-dependent pathway

Finance - Gene products company reports 4th quarter and year end 2004 financial results

Finance - Genetics-focused biopharmaceutical company announces full-year 2004 results

Finance - Healthcare products provider reports Q4 net sales up 26% to $1.2B

Food Safety - Antimicrobial solution effective against 'Campylobacter jejuni,' company says

HIV Prevention - Company announces 50% enrollment in phase III HIV prevention trial in Ghana

HIV Research - Data on investigational HIV compounds presented at CROI

HIV/AIDS Diagnostics - Medical company announces expansion of HIV test kits to China

HIV/AIDS Research - HIV-HCV coinfection should be treated with pegylated interferon combination

HIV/AIDS Research - PRO 2000 shown to inhibit HIV and herpes simplex virus

HIV/AIDS Research - Pharma company announces HIV drug candidate trial results

HIV/AIDS Research - Phase 1 trial results for HIV treatment announced

HIV/AIDS Research - Study of AIDS-blocking pill progressing

HIV/AIDS Testing - Early detection of kidney dysfunction in HIV patients using new marker studied

HIV/AIDS Testing - Utility of virologic assays in HIV management discussed iat conference

HIV/AIDS Therapy - BioScience company announces data from HIV treatment program

HIV/AIDS Vaccine - DermaVir is a new topical vaccine for HIV/AIDS

HIV/AIDS Vaccine - E-communications company teams with U2's Bono to combat AIDS, poverty in Africa

HIV/AIDS Vaccine - HIV genomic RNA sequences in female genital tract and blood reported

HIV/AIDS Vaccine - Innate immunity in experimental SIV infection and vaccination explored

HIV/AIDS Vaccines - Researchers' data advance HIV/AIDS vaccines research

Haemophilus Vaccine - Method to predict interference in combined Hib/DTaP vaccines developed

Hantavirus - Trafficking of Andes and Sin Nombre hantavirus glycoproteins outlined

Hantavirus Vaccine - Viremia delayed in immunized macaques challenged with hantavirus

Hepatitis C Therapy - FDA approves drug combination as first hepatitis C treatment for HIV patients

Human Papillomavirus - Subsequent HPV risk in HIV+ women not lowered by natural infection

Human Papillomavirus Vaccines - Findings in human papillomavirus vaccines provide new insights

Immunotherapy - Cobra inks deal to supply trial material for TNFa Kinoid

Influenza - Healthcare employee vaccination rates could be better

Influenza - Hotline method works to educate public

Influenza - World poorly prepared for next influenza pandemic, scientists warn

Influenza Vaccine - Economic analysis of annual influenza vaccination of children reported

Influenza Vaccine - Epitope analysis for influenza vaccine design reported

Influenza Vaccine - Fluvirin vaccine license reinstated by U.K. regulatory agency

Leishmaniasis Vaccine -  Leishmania membrane proteins are prophylactic against leishmaniasis

Leishmaniasis Vaccine - Drug-sensitive Leishmania vaccine developed

MMR Vaccine - Policies on MMR vaccinations must balance freedoms and responsibilities

MMR Vaccine - Respiratory delivery of MMR vaccine more immunogenic than injection

Malaria Infection -  Plasmodium protein proteolytically processed during cell invasion

Malaria Vaccine -  Plasmodium merozoite surface protein protects against malaria

Malaria Vaccine - Parasite growth rates measured in volunteers challenged with malaria

Malaria Vaccine - Vaccines with DNA and viral vectors possess differential immunogenicity

Malaria Vaccines - Researchers report details of new studies and findings in the area of malaria vaccines

Measles - WHO: Global measles deaths drop 39%

Measles Epidemiology - Measles virus isolated in Croatia during outbreak characterized

Melanoma Vaccine - Mimotope immunization elicits specific antibody response to Mel-CAM

Meningitis Vaccine - Antibodies to polysaccharide of Neisseria meningitidis analyzed

Meningococcal Vaccine - Meningococcal polysaccharide-protein conjugate vaccines reviewed

Mesothelioma Vaccine - Fowlpox vector expressing proteins is active against mesothelioma

Multiple Sclerosis - Multiple sclerosis microarray studies with RPI-78M analysis completed

Multiple Sclerosis Vaccine - Phase 2 study on safety, dosing of vaccine for multiple sclerosis announced

Myeloid Leukemia Vaccine - Chronic myeloid leukemia vaccine improves molecular remission rate, data show

Neisseria Epidemiology - Risk of N. meningitidis high in travelers to Hajj in Saudi Arabia

Newcastle Disease Vaccine - Immunogenicity of Newcastle disease vaccines in chickens compared

Pancreatic Cancer Vaccine - MUC1 vaccine with SB-AS2 adjuvant is safe in pancreatic cancer patients

Pediatric Glioma - Oncoscience AG reports response rate of 35.3% in pediatric glioma trials

Pediatric Vaccines - Cost of child immunization services in urban Bangladesh reported

Peptide Receptor - Anchor profiles of HLA-specific peptides presented

Personnel - International biotechnology company appoints new CEO

Pharmaceutical Research - Scientists' findings show regulation of immune cell memory

Pneumococcal Vaccine - Self-reported pneumococcal vaccination validated through local agencies

Pneumococcal Vaccines - Research add new data to pneumococcal vaccines body of knowledge

Polio Vaccine - Dendritic cells and macrophages are productively infected by poliovirus

Polio Vaccine - Seroprevalence of poliovirus antibody in northern Greece reported

Prion Disease - Trapping prion protein in endoplasmic reticulum impairs maturation

Probiotics - Guidelines are important in developing and using probiotics

Rabies Vaccine - Rabies prophylaxis in malnourished children provides protection

Respiratory Syncytial Virus - Research company expands distribution for monoclonal antibodies against RSV

Rotavirus Epidemiology - Epidemiology of rotavirus G-types circulating in Hong Kong is changing

Rotavirus Vaccine - Distribution of rotavirus serotypes has implications for vaccines

SARS - Researchers publish new studies and findings in the area of SARS

Salmonella Vaccine - Overexpression of Salmonella proteins induces CD4 and CD8 T cells

Smallpox - WHO seeks increase in smallpox vaccines

Smallpox Vaccine - Neutralizing anti-vaccinia antibodies titration method standardized

Smallpox Vaccine - Poxvirus CD8+ T cell determinants aid smallpox vaccine design

Smoking Cessation - New drugs may help you quit smoking

Streptococcus Vaccine - C-polysaccharide in Streptococcus pneumoniae vaccines characterized

Streptococcus Vaccine - Immunity to Streptococcus pneumoniae mediated by MyD88

Streptococcus Vaccines - Studies add new findings to streptococcus vaccines body of knowledge

Theileriosis Vaccine - Timing of live theileriosis vaccine is critical for efficacy

Tuberculosis Vaccine - BCG vaccine protects neonatal calves against M. bovis challenge

Tuberculosis Vaccine - Early BCG vaccination elicits adult-like immune response in calves

Tuberculosis Vaccines - New research in the area of tuberculosis vaccines detailed

Vaccinations - Study says a worrisome number of U.S. children get their shots late

Vaccine Adjuvant - Natural endogenous adjuvants reviewed

Vaccine Adjuvant - Subcutaneous injection of IL-12 induces systemic inflammatory responses

Vaccine Development - Ethics of mandatory childhood immunizations discussed

Vaccine Development - IL-15-independent antiviral function of CD8+ T cells outlined

Vaccine Development - In vivo induced antigen technology reviewed

Vaccine Development - Oral vaccination with biodegradable particulates reviewed

Vaccine Development - Tiered pricing of vaccines is not subsidy

Vaccine Development - Vaccination practices in U.S. emergency departments reviewed

Vaccine Efficacy - Shifts in global immunization goals from 1984 to 2004 reviewed

Vaccine Safety - Pediatric vaccines exert divergent effects on female and male mortality

Vaccine Safety - Thimerosal neurotoxicity associated with glutathione depletion

Vaccines Development - Researchers provide details of new studies and findings in the area of vaccines development

Varicella-Zoster Virus - Polymorphisms to distinguish varicella-zoster virus strains evaluated

Virology - Hepatitis C virus genotypes share similar cell entry properties

Virology - La Crosse virus protein counteracts effects of short interfering RNA

Virology Vaccine - Mucosal immunization induces IgG/IgA responses in CD4+-deficient mice

West Nile Encephalitis Vaccine - Live measles vaccine expressing protects against West Nile encephalitis

West Nile Virus - Colorado health official warns West Nile could be back this year

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