Ebola Virus
Ebola glycoprotein toxicity mediated by dynamin-dependent pathway
Published in Vaccine Weekly, March 30th, 2005
According to recent research from the United States, "Ebola virus infection causes a highly lethal hemorrhagic fever syndrome associated with profound immunosuppression through its ability to induce widespread inflammation and cellular damage. Though GP, the viral envelope glycoprotein, mediates many of these effects, the molecular events that underlie Ebola virus cytopathicity are poorly understood. Here, we define a cellular mechanism responsible for Ebola virus GP cytotoxicity."
"GP selectively decreased the expression of cell surface molecules that...
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Source: Vaccine Weekly (2005-03-30)
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