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Measles

Scientists examine D7, a new measles virus genotype

Published in Vaccine Weekly, April 13th, 2005

Scientists examine D7, a new measles virus genotype.

According to a study from Germany, "Measles virus (MV) infection and vaccination induce long-lasting immunity and neutralizing-antibody responses that are directed against the MV hemagglutinin (H) and the fusion (F) protein. A new MV genotype, D7, emerged recently in western Germany, and rapidly replaced the long-term endemically circulating genotypes C2 and D6.

"Analysis of the H gene of C2, D6, D7 and vaccine viruses revealed uniform sequences for each genotype. Interestingly, a consistent exchange of seven distinct amino acids in the D7 H was observed when compared with residues shared between...

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