HIV/AIDS Vaccines
Studies add new findings to HIV/AIDS vaccines body of knowledge
Published in Vaccine Weekly, April 20th, 2005
Study 1: Researchers have achieved productive infection of primary murine astrocytes, lymphocytes, and macrophages by human immunodeficiency virus type 1 in culture.
"A mouse model of human immunodeficiency virus type 1 (HIV-1) infection would be extremely valuable for evaluation of therapies and vaccines; however, multiple blocks to productive infection of NIH 3T3 and other mouse cell lines have been reported. The authors investigated the replication of HIV-1 in primary mouse astrocytes, lymphocytes, and macrophages in culture by infection with intact HIV-1 pseudotyped with...
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Source: Vaccine Weekly (2005-04-20)
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