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Vaccine Vector

Virosome-mediated delivery of protein antigens in vivo described

Published in Vaccine Weekly, April 20th, 2005

Researchers describe virosome-mediated delivery of protein antigens in vivo in a recent issue of Vaccine.

"Induction of CTL responses against protein antigens is an important aim in vaccine development. In this paper we present fusion-active virosomes as a vaccine delivery system capable of efficient induction of CTL responses in vivo. Virosomes are reconstituted viral membranes, which do not contain the genetic material of the virus they are derived from. Foreign macromolecules, including protein antigens, can be encapsulated in virosomes during the reconstitution process," investigators in the Netherlands report.

"Functionally reconstituted...

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