Vaccine Weekly

Cancer Vaccine - General cancer vaccine that targets survivin developed

HIV/AIDS Vaccine - Clustered epitopes of Gag-Pol fusion protein enhance immunity against HIV

Leukemia Vaccine - Protein kinase blockade stops change of myeloid blasts into dendritic cells

Lymphoma Vaccine - Rapid expression of vaccine proteins for B-cell lymphoma developed

Salmonella Vaccine - Oral DNA vaccine developed using stabilized eukaryotic expression plasmids

Alzheimer Disease - Recent findings in Alzheimer disease provide new insights

Apoptosis - Bovine leukemia virus involved in induction and inhibition of apoptosis

Apoptosis - Cancer cell apoptosis induced via Apo2L/TRAIL

Apoptosis - Intracellular overproduction of apolipoprotein L6 induced apoptosis

Apoptosis - Peripheral-type benzodiazepine receptor ligands amplified neuronal apoptosis

Apoptosis - Resveratrol regulated PKC alpha and delta to inhibit growth and induce apoptosis

Cancer Vaccines - Recent findings in cancer vaccines described

Awards - Vaccine researchers receive Discoverers Award from pharmaceutical industry

Bacteriology - Antigen presentation and recognition in bacterial infections reviewed

Brain Cancer - Double-platinum chemotherapy with etoposide treated metastatic brain tumor

Breast Cancer Research - Copper and zinc induced apoptosis in breast cancer cells

Breast Cancer Therapy - Single-agent trastuzumab show promise for breast cancer

Breast Cancer Treatment - Paclitaxel containing less Cremophor EL as first-line therapy for breast cancer

Cancer Vaccines - Research in cancer vaccines provides new insights

Breast Cancer Vaccine - Structural consequences of increasing repeats in MUC1 tumor antigen reported

Breast Cancer Vaccines - Research add new data to breast cancer vaccines body of knowledge

Business Update - Diagnostic testing company expands distribution network to Central America

Business Update - Immunology-focused biotechnology company updates clinical development plans

Business Update - Rapid flow-through diagnostic tech. provider upgrades system to ISO standard

Cancer Cell Apoptosis - Tumor cells sensitized to apoptosis by selective inhibition of specific Akt/PKB

HIV/AIDS Vaccines - Reports advance knowledge in HIV/AIDS vaccines research

Cancer Cell Inhibitors - (5R)-thiolactomycin used to develop new inhibitors of type I fatty acid synthase

Cancer Cell Inhibitors - Novel inhibitors of human histone deacetylases discovered

Cancer Cell Morphogenesis - Tetraspanin CD82 attenuated cellular morphogenesis

Cancer Cell Survival - H-RAS and K-RAS associated with cell survival

Cancer Drugs - Extravascular transport of drugs in tumor tissue examined

Cancer Drugs - Hsp90 and Cdc37 nominated as possible cancer drugs

HIV/AIDS Vaccines - Researchers describe findings in HIV/AIDS vaccines studies

Cancer Immunotherapy - Fusion protein fights cervical cancer in murine models

Cancer Prodrugs - Formaldehyde and butyric acid exhibited anticancer activity

Cancer Risks - Fanconi anemia led to increased cancer risk

Cancer Risks - Reduction of E2F/DP activity might increase risk of cancer

Cancer Survival - Increase in S100A4 associated with decrease in cancer survival

Cancer Therapy - Antitumor activity of measles virus studied

HIV/AIDS Vaccines - Researchers report details of new studies and findings in the area of HIV/AIDS vaccines

Cancer Therapy - Human MUC1 oncoprotein regulated p53-responsive gene transcription

Cancer Therapy - Novel mechanism of checkpoint abrogation conferred by Chk1 downregulation

Cancer Therapy - Silatecan DB-67 showed promise in treating cancer

Cancer Therapy - Transcription factor 3 contributed to curcumin's proapoptotic effect

Cancer Vaccine - DNA vaccine-induced lymphoma protection dependent on anti-idiotype antibodies

Cancer Vaccine - Majority of women accept cervical cancer vaccine for self, children, study shows

Cancer Vaccine - Mass spectrometry used to detect specific MHC class I peptide antigens

Cancer Vaccine - Monocyte-derived dendritic cells present malignant glioma tumor cell lysates

Cancer Vaccine - N-modified GM3 antigens synthesized as therapeutic cancer vaccines

Cancer Vaccines - New research in the area of cancer vaccines detailed

Cerebro-Ventricular Grafting - Alzheimer pathology modulated by hybridoma cells expressing A-beta antibodies

Chemotherapy - Mitotic spindle checkpoints targeted in topoisomerase-based chemotherapy

Collaborations - Agreement signed to develop TB vaccine

Collaborations - Biopharmaceutical manufacturer collaborates to develop oral vaccination

Collaborations - Partnership works toward increasing medicine access in poor countries

Collaborations - Research collaboration with International AIDS Vaccine Initiative announced

Colon Cancer - New insights used for redefining the subcellular location and transport of APC

Colorectal Cancer - Myricetin inhibited enzyme activity in colorectal carcinoma cells

DNA Tumor Viruses - Hope placed in DNA tumor viruses to help understand cancer cell programming

DNA Vaccine - Monoclonal antibody to cytochrome P4507B1 detected after cDNA immunization

Drug Delivery - Polyethylene glycol shifts the dynamics of liposomal clearance

Drug Development - Anthrax antibody data presented at biodefense meeting

E. Coli Vaccine - Pellet formulation of F4 fimbriae for E. coli vaccine developed

Encephalomyelitis Vaccine - Targeting Fn14 signaling protects against autoimmune encephalomyelitis

Finance - Maker of vaccines for cancer, AIDS reports increased revenues for Q4 and year

Finance - RNAi-focused company reports Q4 net loss of $5.8 million

Gafikemia Vaccine - Bacterium causing gafikemia induces resistance to infection in lobsters

HIV/AIDS Research - Pharma company submits two new filings of antiretrovirals to WHO

HIV/AIDS Vaccine - Biotech company to collaborate with International AIDS Vaccine Initiative

HIV/AIDS Vaccine - Dendritic cell vaccine confers partial protection against HIV-1

HIV/AIDS Vaccine - T-cell engineering by T-cell receptor with HIV-1 gp120 specificity reported

HIV/AIDS Vaccines - Dosing begins in phase I trial of CCR5 mAb in patients with HIV-1