Virology Vaccine
Vaccinia kinase features aid elucidation of virion morphogenesis mechanism
Published in Vaccine Weekly, April 27th, 2005
According to published research from the United States, "The vaccinia virus F10 protein is one of two virally encoded protein kinases. A phenotypic analysis of infections involving a tetracycline-inducible recombinant (vDeltaiF10) indicated that F10 is involved in the early stages of virion morphogenesis, as previously reported for the mutants ts28 and ts15. The proteins encoded by ts28 and ts15 have primary defects in enzymatic activity and thermostability, respectively. Using a transient complementation assay, we demonstrated that the enzymatic...
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Source: Vaccine Weekly (2005-04-27)
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