Alzheimer Disease
Recent findings in Alzheimer disease provide new insights
Published in Vaccine Weekly, April 27th, 2005
Study 1: Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.
According to recent research from the United States, "Passive immunization with an antibody directed against the N terminus of amyloid beta (A-beta) has recently been reported to exacerbate cerebral amyloid angiopathy (CAA)-related microhemorrhage in a transgenic animal model. Although the mechanism responsible for the deleterious interaction is unclear, a...
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Source: Vaccine Weekly (2005-04-27)
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