Susan Hasty, Publisher
Table of Contents . . . May 4th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Vaccine Weekly | Other Publications
Influenza Vaccine - Double-stranded RNA poly(I:C) enhances influenza vaccine protection
Tuberculosis Vaccine - Mycobacterium tuberculosis proteomes analyzed for vaccine epitopes
Tuberculosis Vaccine - Nasal boost improves primary BCG-induced protection against TB
Vaccine Development - Single-stranded RNA that stimulates CD14+CD11c+ monocytes identified
AIDS Research - Initiating ART in primary SIV may lead to mucosal immune system restoration
Adenovirus - Interaction of adenovirus protein with packaging sequences examined
Anticancer Therapy - Inhibitory effects of anticancer peptide from Mercenaria examined
Antitumor Activity - Antitumor activity of an ethanol extract of Nigella sativa seeds
Antivenom - Equine monovalent and polyvalent snake antivenoms compared
Apoptosis - Apoptosis in neutrophils studied, role of protein phosphatase 2A defined
HIV/AIDS Vaccines - Reports add new data to HIV/AIDS vaccines research
Apoptosis - E1A activated transcription of p73 and Noxa to induce apoptosis
Apoptosis - Effect of antineoplastic ether lipid compared with homologous compounds
Apoptosis - Impact of FASL-induced apoptosis on the elimination of tumor cells by NK cells
Apoptosis - Stearoyl-CoA desaturase protein and activity levels associated with apoptosis
Apoptosis - Tbx3 expression related to apoptosis and cell proliferation in rat bladder
Autoimmune Disease - Immune disease-focused biopharm company acquires assets for monoclonal antibody
Malaria Vaccines - Recent studies add new data to malaria vaccines research
Biological Therapy - Transfected B cells defeat problems linked to dendritic cell-related therapy
Birth Defects - DLC-1 deemed essential for embryonic development
Bovine Viral Diarrhea Virus - Cellular insertion in NS2 gene of BVDV is potential pathogenic marker
Breast Cancer - Conjugated linoleic acid reduced murine mammary tumor cell
Breast Cancer - New treatment developed for BRCA1/2-associated disease
Breast Cancer - PEA3 and AP-1 involved in regulation of breast cancer-linked gene, mammaglobin
Malaria Vaccines - Researchers describe findings in malaria vaccines studies
Brucellosis - Researcher reviews brucellosis at dawn of the 21st century
Business & Finance - Drug company concludes credit agreements to refinance Aventis acquisition
Business Update - Company focused on HIV prevention receives grant for product development
Business Update - Genetronics announces name change
Business Update - Influenza-focused drug company awarded $97 million U.S. HHS vaccine contract
Business Update - Microbial identification system meets U.S. FDA good manufacturing practices
Malaria Vaccines - Researchers provide details of new studies and findings in the area of malaria vaccines
COX-2 - Skin tumors studied, role of kinases clarified
Cancer Therapy - Personalized melanoma vaccine trial commences
Cancer Vaccine - Hypothetical proteins detected in 10 individual human tumor cell lines
Cancer Vaccine - Modification of tumor antigen induced divergent T lymphocyte responses
Cancer Vaccine - Monoclonal antibody fused to GM-CSF breaks tolerance to CEA
Cancer Vaccines - MHC epitope presentation by cancer vaccines is transporter-independent
Melanoma Vaccines - Studies advance knowledge in melanoma vaccines research
Cancer Vaccines - New findings in the area of cancer vaccines detailed
Cervical Cancer - p27(Kip1) downregulated telomerase activity in human cervical cancer
Childhood Immunization - Combination vaccine produces lower immune response
Clinical Trials - Phase I study of novel oral cancer compound, INCB7839, begins
Cryptococcus - MAT mating types of Cryptococcus neoformans stimulate B cells
Cytomegalovirus - Cytomegalovirus-specific CTLs enhanced by recombinant virus
Pneumococcal Vaccines - Researchers' work adds to pneumococcal vaccines body of knowledge
DNA Research - Italian patent application filed on transrenal DNA technology to detect HIV, TB
Drug Development - Computer modeling allows vaccine design by computer
Drug Resistance - Targeting senescence pathways reversed drug resistance in cancer
Epirubicin - Effects of epirubicin on proliferation of Ehrlich ascites carcinoma cells
Finance - Respiratory-focused company reports year end results of near 100% net increase
Flavonoids - Flavonoids-induced apoptosis tied to inhibition of fatty acid synthase activity
Pneumococcal Vaccines - Studies add new findings to pneumococcal vaccines body of knowledge
Gangrene - Clostridium perfringens alpha-toxin characterized
HIV/AIDS Pathogenesis - HIV-1 catalytic core domain residues important for HIV-1 replication/integration
HIV/AIDS Prevention - Foundation, J&J to initiate programs to prevent PMTCT of HIV in 7 countries
HIV/AIDS Therapy - UK government lauded for microbicide development support
HIV/AIDS Vaccine - CTL programming allows soluble antigen to generate secondary CTL
HIV/AIDS Vaccine - Data on DNA-binding protein to correct human genes published online in 'Nature'
Tuberculosis Vaccines - Researchers' findings advance tuberculosis vaccines research
HIV/AIDS Vaccine - HLA peptide processing by dendritic cells from HIV+ patients examined
HIV/AIDS Vaccine - Immune-based biopharmaceutical company auditors note going-concern qualification
HIV/AIDS Vaccine - Segments of consecutive AA residues of HIV gp120 proposed as vaccine candidates
HIV/AIDS Vaccine - Vaccine-elicited antibodies reduce viremia in SIV-challenged macaques
HIV/AIDS Vaccines - Findings advance knowledge in HIV/AIDS vaccines research
Hematology - New findings in hematology described
Hepatitis B Vaccine - Immune response to hepatitis B DNA vaccine improves upon protein boosting
Hepatitis E Virus - Interactions involved in assembly of hepatitis E virus capsid analyzed
Herpesvirus Vaccine - Genital herpes protection linked to vagina-associated lymphoid tissue
Herpesvirus Vaccines - Recent findings in herpesvirus vaccines provide new insights
Human Papillomavirus - Investigational HPV vaccine reduced infection and disease in study
Human Papillomavirus - Papillomavirus virus-like particles activate Langerhans cells
Human Papillomavirus Vaccines - Researchers publish new studies and findings in the area of human papillomavirus vaccines
Immunology - Natural killer cells examined, control of adaptive immune responses defined
Influenza Vaccine - Company's cell-culture technology to be part of U.S. flu vaccine program
Influenza Vaccine - U.S. HHS awards $97M contract to develop cell-culture-based influenza vaccine
Kidney Cancer - von Hippel-Lindau (VHL) tumor suppressor protein sensitized cancer to bortezomib
Legal Issues - Gen-Probe prevails in arbitration concerning viral diagnostics collaboration
Leishmaniasis Vaccine - Leishmania chagasi proteinase developed to diagnosis leishmaniasis
Leishmaniasis Vaccine - IL-9 is a susceptibility factor in Leishmania major infection
Leukemia - Pomolic acid triggered mitochondria-dependent apoptotic cell death in leukemia
Liver Damage - Contrasting effects of telomere shortening explored
Lung Cancer - Sulindac enhances adenoviral vector-mediated apoptosis in lung cancer
Malaria Vaccine - Antibody response to Plasmodium vivax apical membrane antigen reported
Malaria Vaccine - Spleen important in malaria
Malaria Vaccines - Recent findings illuminate research in malaria vaccines
Measles Vaccine - Measles-specific cytokine response after measles vaccinations reported
Measles Virus - Measles virus rescued from cloned cDNA using SLAM-expressing cells
Melanoma - DSMB recommends discontinuation of Canvaxin phase III trial for melanoma
Melanoma - Eugenol caused melanoma growth suppression through inhibition of E2F1
Melanoma Vaccine - Anti-vaccine T cells increased after vaccination with MAGE-3 protein
Melanoma Vaccines - Findings advance knowledge in melanoma vaccines research
Meningitis Vaccines - Research add new data to meningitis vaccines body of knowledge
Nipah Virus - Extra-cellular domain of Nipah virus glycoprotein purified
Oncology - Alterations of pre-mRNA splicing in cancer analyzed
Paracoccidioidomycosis - Active formamidase of Paracoccidioides brasiliensis characterized
Parasitology - Actin-based motility of intracellular pathogens reviewed
Personnel - Former Fleishman-Hillard executive joins vaccine company
Personnel - Vaccines company announces addition to board of directors
Pneumococcal Vaccine - Pneumococcal antibodies require CD1 molecules and CD8+ cells
Pneumococcal Vaccines - Research add new data to pneumococcal vaccines body of knowledge
Polio Vaccine - Childhood mortality after oral polio immunization campaign reported
Prostate Cancer - Inhibition of IkappaB kinase activity promoted apoptosis in prostate cancer
Prostate Cancer - Phase I/II clinical trial begins in patients with recurrent prostate cancer
Protein Expression - Link between protein structure and solubility on expression discussed
Protein Kinase - Ilimaquinone studied, role on gap junctional communication defined
Protein Synthesis - eIF2 alpha phosphorylation and stress perception in CHO cells examined
Pseudopodia - Proteomic characterization of harvested pseudopodia reported
Rheumatic Fever - Myocardial tissue damage occurs in rabbits injected with streptococci
Rheumatology - Therapy and dosing for pediatric rheumatic disorders reviewed
SARS Virus - Recent findings in SARS virus described
Salmonella Vaccines - Research in salmonella vaccines provides new insights
Shigellosis - Tyrosine kinase signaling and effectors of Shigella invasion reviewed
Smallpox Vaccines - Researchers publish new studies and findings in the area of smallpox vaccines
Snow Mountain Virus - Immunity following Snow Mountain virus challenge examined
Streptococcus Vaccines - Reports add new data to streptococcus vaccines research
Theileriosis Vaccines - Recent studies add new data to theileriosis vaccines research
Tuberculosis Vaccine - Advancing TB vaccines to phase I clinical trials in U.S. outlined
Tuberculosis Vaccine - Control of human host immunity to mycobacteria reviewed
Tuberculosis Vaccine - Expanding BCG antigenic repertoire improves protection against TB
Tuberculosis Vaccine - TB vaccines for the world reviewed
Tuberculosis Vaccines - Researchers' data advance tuberculosis vaccines research
Vaccine Development - Antibodies adsorbed to aluminum adjuvants characterized
Vaccine Development - Hepatitis B virus capsid protein is a potent antigen carrier for vaccines
Vaccines Adjuvant - New findings in the area of vaccines adjuvant described
Vaccinia Virus Vaccine - Poxvirus-specific CD8+ CTL epitopes with distinct profiles identified
Virology - MyD88 expression required for cross-presentation of viral antigens
Virology - Sendai virus nucleocapsid-like particles generated in yeast
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