Anthrax

Studies advance knowledge in anthrax research

Published in Vaccine Weekly, May 25th, 2005

Anthrax research advances have been reported from the United States.

Study 1: According to recent research from the United States, "We have developed a therapeutic for the treatment of anthrax using an affinity-enhanced monoclonal antibody (ETI-204) to protective antigen (PA), which is the central cell-binding component of the anthrax exotoxins."

"ETI-204 administered preexposure by a single intravenous injection of a dose of between 2.5 and 10 mg per animal significantly protected rabbits from a lethal aerosolized anthrax spore challenge (similar to 60 to 450 times the 50% lethal dose of Bacillus anthracis Ames). Against a similar challenge,...

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Source: Vaccine Weekly (2005-05-25)

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