Susan Hasty, Publisher
Table of Contents . . . June 1st, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Vaccine Weekly | Other Publications
Cancer Vaccines - Programming hematopoietic stem cells provides long-term T cell immunity
Cancer Vaccines - Tumor proteome suppressed by an adenovirus-based skin patch vaccine
HIV/AIDS Vaccines - Safety of HeLa-based cell substrates in HIV vaccine reported
Pneumonic Plague Vaccine - Yersinia pestis protein epitopes recognized by CD4 T cells reported
Smallpox Vaccine - Structure of poxvirus L1 protein elucidated
Adenovirus - Company introduces upgraded version of kit for adenovirus purification
Adenovirus - New findings in the area of adenovirus detailed
Adverse Drug Reaction - FDA to change regulations regarding side-effect information in drug ads
Alzheimer Disease - Prospects for disease-modifying therapy of Alzheimer disease outlined
Amyotrophic Lateral Sclerosis - FDA grants orphan-drug status to small-molecule drug candidate arimoclomol
Apoptosis - Citrus limonoids induced apoptosis in human neuroblastoma cells
Cancer Vaccines - New research in the area of cancer vaccines detailed
Asthma Pathogenesis - Transfer of T-helper cell clones attenuates asthmatic phenotype
Avian Influenza - Politicians bury their heads in the sand while global flu threat mounts
Awards - Charles Farthing receives 2005 HIV Leadership Award as 'outstanding physician'
Awards - Filtration device company nominated for award for aiding Indian vaccine makers
Awards - U.S. Army research group awards $4.09 million for development of malaria vaccine
Bioterrorism - FDA approves Vaccinia immune globulin for some reactions to smallpox vaccine
Breast Cancer - HIV Tat targeted into mitochondria of breast cancer cells
Breast Cancer - Imatinib mesylate monotherapy used to treat metastatic breast cancer
Breast Cancer - Melatonin-estrogen interactions related to breast cancer
Breast Cancer - Survey shows communication trends between cancer survivors and health providers
Business & Finance - Melanoma-focused pharmaceutical company reports Q1 2005 financial results
Business Update - Developer of biological products issues correction for computational error
Cancer Drugs - Manumycin A-induced apoptosis enhanced by methoxyamine in myeloid leukemia cells
Cancer Therapy - Antineoplastic potential of TNF discussed
Cancer Therapy - Continual progress in cancer research yields promising cancer therapies
Cancer Therapy - Skin cancer treatments focus on surgical approaches, new noninvasive therapies
Cancer Therapy - Studies describe new findings in cancer therapy research
Cancer Vaccines - Cancer immunotherapy targets minor histocompatibility antigens
Cancer Vaccines - Dendritic-cell-based therapeutic vaccination against cancer reviewed
Cancer Vaccines - Migration of dendritic-cell-based cancer vaccines reviewed
Cancer Vaccines - Native blood dendritic cells possess tumoricidal potential
Cancer Vaccines - New findings in the area of cancer vaccines detailed
Cancer Vaccines - Role of CD4+ cells and antibodies in breast cancer protection described
Cancer Vaccines - Support for immunological mechanism of cancer vaccines research published
Chagas Disease - Trypanosoma cruzi-infected patients have varied antibody responses
Chickenpox Vaccine - Failure to get catch-up vaccinations causes varicella outbreak
Childhood Immunization - Parents who don't vaccinate their children may believe vaccines cause harm
Chlamydial Infections - Genome sequencing for Chlamydophila abortus may help curb infections
Colon Cancer - IL-8 promotes cell proliferation in human colon carcinoma cells
DNA Vaccines - Researchers describe findings in DNA vaccines studies
DPT Vaccines - Studies advance knowledge in DPT vaccines research
Drug Development - Fragile U.S. vaccine system needs improvement despite dramatic gains in health
Drug Development - Is the vaccine industry ailing?
Drug Development - New study compares influenza vaccine schedules in children
Ebola Vaccine - CD8-mediated protection against Ebola infection is perforin dependent
Ebola Vaccine - Single-shot outbreak vaccine provides protection against 'Ebola' in animal study
Emphysema - Animal model of autoimmune emphysema presented
Endotoxemia - Phospholipid emulsion neutralizes endotoxin in healthy volunteers
Epstein-Barr Virus - EBI3 may have role in regulating antiviral or antitumoral immune response
Finance - Biopharma reports Q1 net loss of $9.7 million
Finance - Biotech company focused on infectious disease, cancer reports Q1 2005 results
Finance - Monoclonal antibody-focused biotechnology company reports Q1 2005 results
Finance - NIAID awards first $27 million using new bioshield authorities
Foot and Mouth Disease - Immune response against peptides from foot-and-mouth disease analyzed
Foot and Mouth Disease - Inhibitory potential of RNAs against foot-and-mouth disease evaluated
Gastric Cancer - H. pylori+enhanced mucosal IL-1beta production increases gastric cancer risk
Gastroenterology - Cases of early-stage carcinoids of the gastrointestinal tract analyzed
Gastroenterology - Gastrointestinal stromal tumor treated with imatinib
Gene Expression - Octamer/Sox elements required for cis regulation of Nanog gene expression
Group B Streptococcus - Structure of group B Streptococcus capsular polysaccharide determined
HIV/AIDS Pathogenesis - Each genomic RNA in HIV-1 heterozygous virus generate new virions
HIV/AIDS Pathogenesis - Single amino acid substitution controls HIV-1 Vif-dependent blocking of APOBEC3G
HIV/AIDS Research - EcoHIV murine model used to study systemic HIV-1 infection
HIV/AIDS Research - New pharmacokinetic data on taking Lexiva with Nexium released
HIV/AIDS Vaccine Development - Carbohydrate antigens targeted in HIV vaccine development
HIV/AIDS Vaccines - Business response to AIDS group selected to provide focal point for fund
HIV/AIDS Vaccines - New findings in HIV/AIDS vaccines described
HIV/AIDS Vaccines - Phase 1 trial of gene therapy treatment for HIV, plan for phase 2 study reported
Healthcare Coverage - Americans willing to pay more for greater vaccine coverage
Healthcare Coverage - Insurance company introduces health portfolio
Hepatitis B Vaccine - HBsAg-HBIG complex vaccine elicits potent anti-hepatitis immune response
Human Papillomavirus - High-risk mucosal HPV infections during infancy and childhood reviewed
Human Papillomavirus - Immune control of HPV-associated anogenital disease reviewed
Immunology - Deletion of antigen-specific T cells leads to long-term tolerance
Immunology - Lymphocyte subsets in infants analyzed by flow cytometry
Immunology - New findings in the area of immunology described
Influenza - Pediatric clinical study of needle-free flu vaccine delivery device underway
Influenza Epidemiology - Influenza in travelers to tropical and subtropical countries determined
Influenza Vaccine - Influenza vaccinations would benefit university students
Influenza Vaccine - Some evidence of link between neuroticism and antibody response found
Influenza Vaccine - Vaccination strategies for pandemic influenza optimized
Influenza Vaccines - Researchers publish new studies and findings in the area of influenza vaccines
Influenza Virus - Reappearance of influenza B/Victoria/2/87-lineage viruses reported
Information Technology - HIV-products developer re-launches website with expanded investor information
Legal Issues - Court dismisses class-action suit against vaccine company
Lung Cancer - Expression of TARSH gene in MEFs senescence implicated in human lung cancer
Malaria - Prostaglandin E-2 production impaired in children with cerebral malaria
Malaria - Research in malaria provides new insights
Malaria Prevention - 10 years before malaria vaccine is ready for widespread use
Measles Vaccines - Researchers report details of new studies and findings in the area of measles vaccines
Melanoma Vaccine - Stat3 activity in melanoma cells affects NO-mediated antitumor effects
Meningitis B Vaccine - Companies form collaboration to pursue research for meningitis B vaccine
Meningitis Vaccine - Variation reported in meningococcal PorA outer membrane protein
Mergers & Acquisitions - Cancer product development company completes acquisition of DELEX
Mergers & Acquisitions - Company to be acquired by GSK; shareholders get $4.40 per share in cash
Mergers & Acquisitions - GlaxoSmithKline announces acquisition
Monoclonal Antibodies - Number of BAT/CD3 cells appear to vary by cancer type
Mycobacterium Tuberculosis - MTB ESAT-6 gene products modify mycobacteria and immune system interaction
Mycobacterium Tuberculosis - Molecular basis of nitric oxide detoxification mechanism in MTB investigated
Neurofibromatosis - NF2 gene mutation detected in 100% of inherited cases via multiple techniques
Oncology - Researchers report details of new studies and findings in the area of oncology
Ovarian Cancer - Increase in antibodies to MUC1 associated with reduced cancer risk
Pediatric Vaccines - Pediatric immunization rates linked to physician reimbursement levels
Personnel - Henk Kocken, PhD, named VP for quality systems by biopharmaceutical company
Personnel - Zbigniew Wlwszek, PhD, appointed chief scientific officer of biotech company
Pertussis - Boarding school outbreak of pertussis in adolescents reported
Pertussis - FDA approves Boostrix, a new U.S. vaccine for adolescents against pertussis
Pneumococcal Vaccine - Pneumococcal vaccination effective for elderly people in Spain
Pneumococcal Vaccine - Vaccine does not induce lasting IgA response against otitis media
Pneumonia Vaccine - Pneumococcal and influenza vaccines effective for preventing pneumonia
Prostate Cancer - Pharmacokinetics of isotope-labeled antibody specific for PSA reported
Prostate Cancer - Secondary ellagic acid therapy in HRPC patients on standard chemotherapy tested
Quality Assurance - New consensus ambulatory performance measures established by collaborative group
Respiratory Syncytial Virus - RSV prevention can be guided by web-based early warning system
Shingles - Pharmaceutical co. submits biologics license application for shingles vaccine
Skin Cancer - Low-dose retinoids prevented cutaneous SCC in organ transplant recipients
Stem Cell Research - Antigen encounter at stem cell transplantation enhances T-cell response
Stem Cell Transplantion - Guide for vaccination of stem cell transplant recipients released
Streptococcus Vaccine - Streptococcus gordonii strain shows promise as vaccine
Streptococcus Vaccine - Role of TNF during infection with Streptococcus pneumoniae reviewed
Tuberculosis Vaccine - Successful TB vaccines need to be immunoregulatory rather than Th1-boosting
Tuberculous Meningitis - BCG protects against tuberculous meningitis in Indian children
Tularemia Vaccine - Efficacy of live attenuated tularemia vaccine evaluated
Tumor Suppression - AP-1 dimers regulated transcription of p14/p19(ARF) tumor suppressor gene
Tumorigenesis - DNA damage response used as anti-cancer barrier in early human tumorigenesis
Tumorigenesis - Hematopoietic cells regulate angiogenic switch during tumorigenesis
Vaccines Adjuvant - Findings in vaccines adjuvant provide new insights
Virology - Reports describe recent advances in virology research
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