Tumorigenesis
Hematopoietic cells regulate angiogenic switch during tumorigenesis
Published in Vaccine Weekly, June 1st, 2005
According to published research from Japan, "Hematopoietic cells (HCs) promote blood vessel formation by producing various proangiogenic cytokines and chemokines and matrix metalloproteinases. We injected mouse colon26 colon cancer cells or human PC3 prostate adenocarcinoma cells into mice and studied the localization of HCs during tumor development. HCs were distributed in the inner tumor mass in all of the tumor tissues examined; however, the localization of HCs in the tumor tissue differed depending on the tumor cell type. In the case of colon26 tumors, as the tumor grew, many mature HCs...
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Source: Vaccine Weekly (2005-06-01)
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