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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . June 8th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Helicobacter Vaccine - Antibodies against Helicobacter pylori produced in egg yolks

Malaria Vaccine -  Plasmodium berghei polypeptide plus adjuvant elicits immune response

Malaria Vaccine - Poxviruses enhance T cell-mediated protection against malaria

Respiratory Syncytial Virus - Fusion of DsbA to RSV epitope prolongs virus-specific CTL responses

Vaccine Vector - Human adenovirus type 11 developed as gene transfer vector

Acute Myeloid Leukemia - Dominant negative effects of AML1/ETO may be important for AML pathogenesis

Allergy Vaccine - DNA vaccine encoding Der p 2 allergen prevents allergic inflammation

Alzheimer Disease - Interrupted vaccine study yields hopeful results

Anthrax Vaccine - Post-attack anthrax vaccination more cost-effective than pre-attack

Bioterrorism - HHS awards BioShield contract for AVA anthrax vaccine

Bladder Cancer - Noncisplatinum combination used in metastatic transitional cell carcinoma

HIV/AIDS Vaccines - Researchers' findings advance HIV/AIDS vaccines research

Breast Cancer - Endoxifen showed tamoxifen-like, anti-estrogenic effects in breast cancer cells

Cancer Therapy - Company licenses anti-CD55 antibody cancer therapy from research technology

Cancer Therapy - Immune-response strategy to be tested for use against cancer

Cancer Vaccine - Small interfering RNAs silence Fas-ligand gene in basal cell carcinoma

Cancer Vaccines - Findings in cancer vaccines provide new insights

Cervical Cancer - Data presented on vaccine response in adolescents

Tuberculosis Vaccines - New findings in tuberculosis vaccines described

Cervical Cancer - FDG-PET used for management of cervical and ovarian cancer

Clinical Trials - Phase 2 monotherapy trial of oral entry inhibitor HIV drug initiated

Crohn Disease - MMR vaccine does not increase risk of Crohn

Cytomegalovirus - Cytomegalovirus studied, nature of post-transplantation protection defined

Diagnostics - New data on cervical screening with HPV and Pap tests discussed at conference

Disease Associations - Dengue virus receptor complex studied, role of heat shock proteins defined

Tuberculosis Vaccines - New research in the area of tuberculosis vaccines detailed

Disease Outbreaks - Integrated health campaign saves African children from malaria and measles

Finance - Antoimmune-focused pharmaceutical company reports first quarter 2005 results

Finance - Immunotherapeutics-focused biotech company announces first quarter 2005 results

Finance - Immunotherapy maker announces increased revenue, lower losses in Q1

Finance - Pharmaceutical company reports first quarter 2005 results

Finance - Pharmaceutical company reports unaudited results for first quarter 2005

Finance - Safety needle designer, developer announces first quarter 2005 financial results

Finance - Therapeutics company reports first quarter financial results

Finance - Transdermal science-focused company reports first quarter 2005 financial results

Finance - Vaccine maker reports dip in revenue during Q1

Food Safety - Collaboration established to advance plant-made vaccine platform

Gene Expression - LKLF-regulated genes identified in quiescent CD4+ T lymphocytes

HIV/AIDS Diagnostics - Medical services company begins shipping HIV test kits to China

HIV/AIDS Diagnostics - U.S. FDA gives approval for enhancements to rapid HIV test

HIV/AIDS Drug Development - HIV-inactivating protein isolated from red alga Griffithsia sp

HIV/AIDS Genomics and Genetics - Enfuvirtide resistance mutations affect HIV neutralization

HIV/AIDS Pathogenesis - Critical domain definition required for homophilic sidekick molecule targeting

HIV/AIDS Pathogenesis - HIV-1 capsid cysteine residues regulate oligomerization and CypA-induced changes

HIV/AIDS Prevention - Company donates 100,000 condoms to New York City 'I Know' HIV/AIDs effort

HIV/AIDS Prevention - Pharma company joins fight the HIV/AIDS epidemic in China

HIV/AIDS Vaccine - Clade B vaccine elicits response against conserved epitopes in multiple clades

HIV/AIDS Vaccine Development - Synthetic vaccine antigen construct detects HIV-induced humoral responses

HIV/AIDS Vaccine Research - HIV preventative vaccine program developed a strategy based on lipopeptides

HIV/AIDS Vaccines - New findings in the area of HIV/AIDS vaccines detailed

Hepatitis B - BMA calls for universal childhood vaccination against hepatitis B

Hepatitis B Vaccine - Endoplasmic reticulum targeting sequence augments hepatitis B DNA vaccine

Immunization - Double dose hepatitis B vaccine protects HIV-infected adult patients

Immunology - Findings describe new data in immunology research

Influenza - Flu vaccine shows potential against pandemic flu in preclinical model

Influenza - University study validates higher sensitivity of influenza A+B rapid flu test

Influenza Vaccine - Evolution of anti-influenza vaccination coverage in Spain outlined

Influenza Vaccine - Mutational pattern of influenza B viruses grown in eggs reported

Isoenzymes - Co-expression of glutaminase K and L isoenzymes in human tumor cells

Leucodepletion - Alloimmunization to red blood cells after leucodepletion examined

Liver Metastasis - Continuous hepatic arterial infusion chemotherapy treated liver metastasis

Lung Cancer - Gefitinib used as first-line therapy against advanced or metastatic lung cancer

Malaria - Researchers detail new studies and findings in the area of malaria

Melanoma - Biallelic deletions in INK4 in melanoma associated with decreased survival

Melanoma Vaccines - Reports add new data to melanoma vaccines research

Meningitis Vaccine - Effect of meningococcal vaccine booster on antibody response examined

Mergers & Acquisitions - Vaccine maker expands manufacturing capability with acquisition

Mumps - U.K. is in the grip of a nationwide mumps epidemic

Parkinson Disease - Glucocerebrosidase gene mutations associated with Parkinson disease

Pediatric Vaccine - Nurse training may improve childhood immunization rates in New Zealand

Pneumococcal Vaccine - CD8+ T cells mediate acquired immunity to pneumococcal colonization

Pneumococcal Vaccine - Evaluating media campaign to promote pneumococcal vaccination difficult

Pneumococcal Vaccine - Population-based analysis of pneumococcal disease mortality reported

Prion Disease - Synthetic prion protein peptides slow progression of scrapie

Prion Diseases - Active vaccine prevents mice from developing brain diseases

Product Licensing - Pharmaceutical company exercises option for additional antigen

Psoriasis Therapy - Alefacept for treatment of psoriasis reviewed

Pulmonary Medicine - Genetic profiles divide primary and metastatic squamous cell lung cancers

Respiratory Syncytial Virus - DNA vaccine against respiratory syncytial virus evaluated

Rubella - German measles no longer major public health threat in the United States

SARS Vaccines - Researchers provide details of new studies and findings in the area of SARS vaccines

SARS Virus - New data illuminates research in SARS virus

Smallpox - Smallpox organization marks 25th anniversary of eradication of smallpox

Stem Cell Research - Down-regulation of SSX impairs cell migration and MMP2 expression

Tuberculosis Vaccine - Vaccination strategies against AIDS and tuberculosis needed

Tuberculosis Vaccines - New findings in the area of tuberculosis vaccines detailed

Ulcerative Colitis - Biopharma company begins clinical trial for ulcerative colitis treatment

Vaccine Adjuvant - Avipox-GM-CSF compared to GM-CSF protein as immune adjuvants

Vaccine Adjuvant - Lipopeptides in liposomes promote maturation of human dendritic cells

Vaccine Development - Biotin-streptavidin binding applied for iscom association of immunogens

Vaccine Development - National foundation holds annual conference on vaccine research

Vaccine Development - Recombinant vaccine antigen protects monkeys against hepatitis E infection

Vaccine Safety - Adverse events following hexavalent vaccine reported

Vaccine Vector - Adenovirus cross-reactivity in delayed-type hypersensitivity examined

Vaccine Vector - Baculovirus is highly efficient expression vector

Vaccine Vector - Cross-linked small polyethylenimines deliver DNA to mammalian cells

Vaccine Vector - Tetracycline-regulatable adeno-associated virus vector developed

Vector Development - Complex mosaicism boosts the infectivity of adenovirus type 5-based vectors

Virology - Researchers describe findings in virology studies

Virology Vaccines - Recent findings in virology vaccines described

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