Published in Vaccine Weekly, June 8th, 2005
"The pattern of expression of glutaminase isoenzymes in tumor cells has been investigated to clarify its role in the malignant transformation and the prospect of its use as a clinically relevant factor. Using leukemia cells from medullar blood of human patients and several established human cancer cell lines, we have developed a competitive RT (reverse transcriptase)-PCR assay to quantify simultaneously K-type (kidney-type) and L-type (liver-type) glutaminase mRNAs," scientists in Spain reported.
"Co-expression of both transcripts and higher amounts of L-type mRNA...
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