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Vaccine Development

Biopharma company begins studies of vaccine to produce antistaph antibodies

Published in Vaccine Weekly, June 15th, 2005

Nabi Biopharmaceuticals (NABI) announced that it has initiated bridging and consistency lot studies for its StaphVAX (Staphylococcus aureus Polysaccharide Conjugate Vaccine) under development for the prevention of S. aureus bloodstream infections in at-risk adults.

The bridging study is designed to compare the immune response and safety of the StaphVAX material produced by the company's contract manufacturer with that of the StaphVAX lot from the company's phase III clinical trial in end-stage renal disease (ESRD) patients. The consistency lot study is being conducted in healthy adults to compare the safety and immunogenicity of three commercial lots of...

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