Vaccine Vector
Fractal structure of polycation-DNA complexes reported
Published in Vaccine Weekly, June 15th, 2005
According to published research from the United States, "We used static light scattering to obtain new measurements on the internal structure of aggregated non-viral gene-delivery particles in colloidal suspension. The vector particles are prepared by charge neutralization of plasmid DNA either by poly-L-lysine or by a lipofectin/integrin-targeting peptide. We use established theories of the stability of colloidal particles and fractal concepts to explain the aggregation processes and demonstrate the existence of a new property (fractal...
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Source: Vaccine Weekly (2005-06-15)
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