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Cancer Vaccines

Data advance knowledge in cancer vaccines research

Published in Vaccine Weekly, June 15th, 2005

Cancer vaccines data are the focus of recent research from the United States, Australia and France.

Study 1: Surrogate tumor antigen vaccination induces tumor-specific immunity and the rejection of spontaneous metastases.

According to a study from the United States, "The nonimmunogenic 4T1 murine mammary carcinoma model and a model surrogate tumor antigen (sTA) were employed to explore the possibility of inducing tumor-specific immunity through active immunization in the absence of defined tumor-associated antigens. Immunization of naive mice with protein-based sTA resulted in protection from s.c. challenge, with 4T1 modified to express the sTA...

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