Published in Vaccine Weekly, June 15th, 2005
Study 1: Surrogate tumor antigen vaccination induces tumor-specific immunity and the rejection of spontaneous metastases.
According to a study from the United States, "The nonimmunogenic 4T1 murine mammary carcinoma model and a model surrogate tumor antigen (sTA) were employed to explore the possibility of inducing tumor-specific immunity through active immunization in the absence of defined tumor-associated antigens. Immunization of naive mice with protein-based sTA resulted in protection from s.c. challenge, with 4T1 modified to express the sTA...
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Source: Vaccine Weekly (2005-06-15)
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