SARS Coronavirus
Researchers suggest an effective immunoprophylaxis strategy in outbreak setting
Published in Vaccine Weekly, June 29th, 2005
According to a study from the United States, "In this report, the antiviral activity of 80R immunoglobulin G1 (IgG1), a human monoclonal antibody against severe acute respiratory syndrome coronavirus (SARS-CoV) spike (S) protein that acts as a viral entry inhibitor in vitro, was investigated in vivo in a mouse model. When 80R IgG1 was given prophylactically to mice at doses therapeutically achievable in humans, viral replication was reduced by more than 4 orders of magnitude to below assay limits."
J.H. Sui and associates at the Dana Farber...
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Source: Vaccine Weekly (2005-06-29)
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