Cancer Vaccine
Tumor glycolipids and proteins mediate complement-related cytotoxicity
Published in Vaccine Weekly, July 6th, 2005
According to a study from the United States, "One of several effector mechanisms thought to contribute to antibody efficacy against cancer is complement-dependent cytotoxicity (CDC). Serological analysis of a series of clinical trials conducted over a 10-year period suggested that six vaccines containing different glycolipids induced antibodies mediating CDC whereas four vaccines containing carbohydrate or peptide epitopes carried almost exclusively by mucin molecules induced antibodies that did not mediate CDC."
"To explore this...
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Source: Vaccine Weekly (2005-07-06)
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