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Multiple Sclerosis

FOXP3 identified as gene marker for impaired immune regulation in MS

Published in Vaccine Weekly, July 13th, 2005

The Immune Response Corporation (IMNR) is a biopharmaceutical company focused on immune-based therapy in HIV and multiple sclerosis (MS).

IMNR announced that clinical research conducted by the company in association with Oregon Health & Science University (OHSU) has indicated that FOXP3, a specific genetic marker on T-cells known to be involved in maintaining immune tolerance and regulation of autoimmune diseases, is significantly reduced in patients with MS compared to healthy controls.

These findings, published in the July issue of the Journal of Neuroscience Research, are significant because this deficiency of FOXP3 in MS patients is likely...

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