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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . July 27th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Allergy Medicine - Molecule resembling grass pollen epitopes developed for allergy vaccine

Herpes Zoster Vaccine - Vaccine to prevent herpes zoster and postherpetic neuralgia developed

Melanoma Vaccine - Noncanonical melanoma T cell epitopes identified for cancer therapy

Meningitis Vaccine - Meningococcal epidemiology changed after bivalent vaccine introduced

Tuberculosis Vaccine - Ag85B fusion molecule-based tuberculosis subunit vaccine developed

Adriamycin Nephropathy - Naked DNA encoding MCP-1 and RANTES protects against renal injury

Allergy Medicine - Findings in allergy medicine provide new insights

Alzheimer Disease - Nerve growth factor gene therapy for Alzheimer disease described

Anicemycin - Anicemycin inhibited anchorage-independent growth of tumor cells

Apoptosis - Induction of NO and ROS caused apoptosis in lymphoma cells

Breast Cancer - New findings in the area of breast cancer described

HIV/AIDS Vaccines - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines

Breast Cancer - Phytoestrogens and 17 beta-estradiol inhibited apoptosis in breast cancer cells

Breast Cancer Vaccine - BAT antibody enables DNA vaccine to inhibit Her-2/neu carcinomas

Business Update - Pharmaceutical company signs agreement to distribute Botox in Hungary and Poland

Cancer Vaccine - 5-Fluorouracil enhances efficacy of conditionally replicating herpes

Cancer Vaccine - Adenovirus oncolytic and immunostimulatory tumor therapy assessed

Cancer Vaccine - Dendritic cells efficiently cross-prime tumor antigen-specific T cells

Influenza Vaccines - Researchers' work adds to influenza vaccines body of knowledge

Cancer Vaccine - Electroporation is prime/boost strategy for DNA vaccine against cancer

Cancer Vaccine - Emerging strategies for Epstein-Barr virus-related cancer reported

Cancer Vaccine - Endometrial cancer responds to cancer/testis antigen

Cancer Vaccine - Influenza virosome enhances activity of CEA anticancer vaccine

Cancer Vaccine - Insights into peptide-based vaccine design for cancer therapy presented

Cancer Vaccine - Recent developments in therapeutic cancer vaccines reviewed

Tuberculosis Vaccines - Research in tuberculosis vaccines provides new insights

Cancer Vaccine - TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage

Cancer Vaccines - Reports advance knowledge in cancer vaccines research

Celiac Disease - Antibodies to gluten protein do not cross-react with Bordetella

Cervical Cancer - HPV capsid mutation allows escape from cervical cancer immunity

Cervical Cancer - Survey flags doctor-patient communication gap regarding HPV and cervical cancer

Chickenpox Vaccine - Reduction in herpes-zoster increases benefit of varicella vaccination

Vaccines Adjuvant - Researchers report details of new studies and findings in the area of vaccines adjuvant

Clinical Trials - Clinical study of Aurora kinase inhibitor in hematologic cancers initiated

Clinical Trials - U.S. FDA, research company sign protocol for trial of catheter-linked infections

Collaborations - Collaborations announced for clinical trials in acute ischemic stroke treatment

Collaborations - Joint venture Celltrion to manufacture product for Bristol-Myers Squibb Company

Collaborations - Pharmaceutical companies announce collaboration in small molecule therapeutics

Colon Cancer - Antiproliferative action of water extracts from raspberry seeds analyzed

Vaccines Development - Recent findings illuminate research in vaccines development

Cytomegalovirus Vaccine - Elimination of ie1 attenuates cytomegalovirus virulence

DPT Vaccine - Monitoring of equality in immunization coverage reviewed

Dendritic Cell Vaccine - Elutriation of monocytes for dendritic cell generation reported

Dendritic Cell Vaccine - Immunolipoplexes provide alternative for dendritic cells transfection

Dendritic Cell Vaccine - mRNA transfection enhances dendritic cell immunostimulatory function

Dengue Fever - The cost of dengue fever challenges public health and national economies

Diabetes Therapy - Diabetes care among Puerto Rican adults in New York City assessed

Diabetes Therapy - Transforming growth factor-beta I gene therapy restores beta cell function

Diagnostics - Genetics-focused company contracts with cancer center to develop diagnostic test

Diphtheria Vaccine - MPL enhances antibody response to diphtheria toxin and its subunits

Disease Associations - Human coronavirus NL63 studied, use of SARS coronavirus receptor revealed

Drug Development - Natural human alpha interferon approved for sale in Chile

Echinococcus Vaccine - Immunogenicity of two Echinococcus granulosus antigens reported

Feline Leukemia Virus Vaccine - Neutralizing antibodies against feline leukemia virus protein generated

Finance - Anti-infectives-focused research company secures funding, tests new compounds

Finance - Global health initiative funds project to advance vaccine testing

Foot-and-Mouth Disease Vaccine - DNA vaccine protects against foot-and-mouth disease virus challenge

HIV/AIDS Therapy - U.S. FDA approves new anti-HIV protease inhibitor for use in combination therapy

HIV/AIDS Vaccine - AIDS vaccine development reviewed

HIV/AIDS Vaccine - Aptamers to HIV reverse transcriptase effective in blocking replication

HIV/AIDS Vaccine - HIV gag-specific gamma interferon-expressing cells characterized

HIV/AIDS Vaccine - HIV-1 clade A virus-like particles elicit neutralizing antibodies

HIV/AIDS Vaccine - Mucosal CCR5-reactive antibodies induced as anti-HIV strategy

HIV/AIDS Vaccines - Researchers detail new studies and findings in the area of HIV/AIDS vaccines

Healthcare Access - Weak, inequitable health systems block progress in Asia-Pacific, official says

Hemophilia Therapy - Self-regulating lentiviral vector expresses human factor IX in vivo

Hepatitis B - Study shows effectiveness of hepatitis B treatment

Hepatitis B Vaccine - Non-invasive niosomes offer topical immunization against hepatitis B

Hepatitis B Vaccine Development - Hepatitis B vaccine protects animals against woodchuck hepatitis virus

Herpes Vaccine - Protective immunity to herpes simplex virus type 2 mediated by T-bet

Human Papillomavirus - Diagnostics company received CE mark for Linear Array HP Genotyping Test

Infectious Disease - Researchers seek to build better therapeutic vaccines for chronic infections

Infectious Disease - Texas expands state-mandated vaccines for children in child-care facilities

Inflammatory Bowel Disease - Fueling fire in the gut necessary for immune response

Influenza Vaccine - HAART enhances efficacy of influenza vaccine in HIV-infected patients

Influenza Vaccine - Immunity of single versus booster dose of influenza vaccine compared

Influenza Vaccine - Influenza A/Fujian/411/02 virus growth in chicken eggs improved

Influenza Vaccine - Influenza vaccination attitudes at Canadian cancer center explored

Influenza Vaccines - Reports describe recent advances in influenza vaccines research

Leptospirosis Vaccine - Vaccine against leptospirosis does not slow equine recurrent uveitis

Leukemia Vaccine - Methods to prepare dendritic cells for leukemia immunotherapy presented

Leukodystrophy - Galactocerebrosidase expression attenuates globoid cell leukodystrophy

Liver Cancer - Transplantation of NKT lymphocytes suppresses hepatocellular carcinoma

Lymphoma Vaccine - Immunocytokine is effective against B lymphoma

Malaria - Malaria peptides inducing short-lived antibodies have short structures

Marketing - New Jerseay biotechnoloogy company selects advertising agency

Measles Vaccine - Measles control is possible in areas of widespread HIV infection

Measles Vaccine - Measles vaccine given at 6 months of age elicits long-term protection

Melanoma - Differential effects of selenite and selenate delineated

Melanoma Vaccine - Melanoma antigen cross-reactivity does not predict immunogenicity

Melanoma Vaccine - Peptides isolated by melanoma antibodies have different immunogenicity

Meningitis - Study finds vaccine eliminates HIB disease in Gambia

Meningitis - Vaccination virtually eliminates Hib meningitis in The Gambia

Meningitis Vaccine - Cost effectiveness of meningitis immunization strategies reviewed

Meningococcal Vaccine - Attitudes of parents regarding meningococcal C vaccination reported

Mergers & Acquisitions - Microscience, a U.K.-based vaccine company, acquired

Multiple Sclerosis - Trial of vaccine for MS demonstrates increase in gene marker to track T-cells

Niemann-Pick A Disease - Correction of brain pathology in Niemann-Pick A disease reported

Oral Cancer - Cytotoxicity of phenolic acid phenethyl esters on oral cancer cells evaluated

Pancreatic Cancer - Inositol hexaphosphate proposed as novel treatment for pancreatic cancer

Parainfluenza Vaccine - Live bivalent vaccine for parainfluenza and influenza developed

Parvovirus Vaccine - Fluorescent human parvovirus B19 virus-like particles characterized

Patents - Drug-delivery company gets Mexican patent

Patents - Patent application filed on transrenal DNA technology for infectious diseases

Pediatric Vaccine - Refusal of childhood vaccines among parents investigated

Personnel - Clinical trial data management company names board members

Personnel - Pharma company hires Sr. VP and general counsel, announces promotion

Philanthropy - Health plan provides grant to support HIV education

Pneumococcal - Co-amoxiclav and opsonophagocytosis overcome amoxicillin resistance

Pneumococcal Vaccines - Recent studies add new data to pneumococcal vaccines research

Polio - India near eradication of poliovirus

Prostate Cancer Vaccine - Prostate cancer therapy with inducible caspase and IL-12 described

Prostate Cancer Vaccine - Vaccine therapy for prostate cancer presented

Pseudomonas Vaccine - Vector with OprF epitope in capsid protects against Pseudomonas

Schistosomiasis Vaccine -  Schistosoma japonicum reacts with antisera to other species

Smallpox Vaccine - Cell culture-derived smallpox vaccine developed

Tetanus Vaccine - Tetanus and TBE vaccines do not protect healthy elderly adults

Toxoplasmosis Vaccine -  Toxoplasma gondii proteins protect against tissue cyst formation

Tuberculosis Vaccines - Findings in tuberculosis vaccines provide new insights

Tumor Suppressor - ING4 functioned as tumor suppressor

Vaccine Adjuvant - Adenovirus-HSP72 and CEA-plasmid vaccination prolongs survival

Vaccine Adjuvant - Adjuvant IL-7 and IL-15 improves survival of CD8+ memory cell pool

Vaccine Adjuvant - Beta-chemokines induced by orthophosphorothioate oligodeoxynucleotides

Vaccine Adjuvant - Macrophage-activating lipopeptide-2 directly stimulates B lymphocytes

Vaccine Development - Biotechnology company extends agreement to boost production of flu vaccine

Vaccine Development - Encouraging the development of new vaccines described

Vaccine Development - Factors affecting manufacturers' decisions to produce vaccines reported

Vaccine Development - Pharmaceutical company announces U.S. FDA reviews of investigational vaccines

Vaccine Efficacy - Children with leukemia benefit from DPT and MMR vaccinations

Vaccine Policy - Immunization policy and its implementation in U.K. outlined

Vaccine Vector - Two nonviral gene therapy vectors for somatic integration compared

Vaccines Adjuvant - Researchers provide details of new studies and findings in the area of vaccines adjuvant

Vaccines Development - New data illuminates research in vaccines development

Vector Development - Protein expression using bacterial hemoglobin fusion vector reported

Vector Development - Studies advance knowledge in vector development research

Vector Development - Transduction with viral vectors modulates human dendritic-cell function

Virology Vaccine - Rabbit hemorrhagic disease virus VP60 capsid protein expressed

Virology Vaccine - Use of recombinant viruses as vaccines against viral diseases reviewed

Virology Vaccines - New research in the area of virology vaccines detailed

West Nile Virus - Neutralizing antibodies to West Nile virus characterized

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