Published in Vaccine Weekly, July 27th, 2005
Study 1: The vaccinia virus H2 protein is an essential component of a complex involved in virus entry and cell-cell fusion.
"The vaccinia virus H2R gene (VACWR 100) is conserved in all sequenced members of the poxvirus family and encodes a protein with a predicted transmembrane domain and four invariant cysteines. A recombinant vaccinia virus, in which expression of the H2 protein is stringently regulated, was unable to replicate without inducer. However, under nonpermissive conditions, all stages of virus morphogenesis appeared normal and extracellular virions...
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Source: Vaccine Weekly (2005-07-27)
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