Published in Vaccine Weekly, August 3rd, 2005
"Francisella tularensis is the highly infections agent of tularemia, a disease that can prove fatal in humans. An attenuated live vaccine strain (LVS) of this bacterium is avirulent in man but produces lethal illness in mice. As a step toward understanding the species specificity of the LVS, we compared its interactions with murine and human leukocytes. The bacterium replicated within immune bone marrow-derived macrophages (muBMDM), human monocyte-derived macrophages (huMDM), and freshly...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly