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Leukemia Vaccine

Autologous tumor vaccines benefit some chronic lymphocytic leukemia patients

Published in Vaccine Weekly, August 3rd, 2005

Oxidized autologous tumor vaccines benefit some chronic lymphocytic leukemia patients during the watch and wait phase.

According to a study from Canada: "Based on their activity in patients with advanced stage chronic lymphocytic leukemia (CLL), a phase I/II study was designed to evaluate the feasibility, safety, and efficacy of autologous vaccines made from oxidized tumor cells in patients with earlier stage CLL, and to determine an optimal schedule of injections. Eighteen patients (at risk for disease progression and with white blood cell counts between 15 and 100x106 cells/mL) were injected intramuscularly with 10 mL of oxidized autologous blood (composed...

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