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Complementary & Alternative Medicine

Effects of dosing condition on bioavailability of green tea catechins examined

Published in Vaccine Weekly, August 10th, 2005

Researchers analyzed the effects of dosing condition on the oral bioavailability of green tea catechins after administering polyphenon E in healthy individuals.

"Green tea has been shown to exhibit cancer-preventive activities in preclinical studies. Its consumption has been associated with decreased risk of certain types of cancers in humans," investigators in the United States reported.

"The oral bioavailability of the major green tea constituents, green tea catechins, is low, resulting in systemic catechin levels in humans many fold less than the effective concentrations determined in in vitro systems. We conducted this clinical study to test the...

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