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Hepatitis A

Universal immunization of toddlers in Israel reduces hepatitis A rates

Published in Vaccine Weekly, August 10th, 2005

A national immunization program for infants in Israel has resulted in a 95% reduction in overall hepatitis A incidence, according to a new study.

Until 1999, Israel was considered a country with intermediate hepatitis A virus endemicity (a disease constantly present to greater extent in a particular locality). Although the overall incidence has been progressively decreasing since the 1960s, the annual reported incidence during the 1992-1998 period ranged from 33-70 per 100,000 population, with marked fluctuations.

Reports of outbreaks, especially those involving young children, increased. Because most young children have asymptomatic or unrecognized...

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