Published in Vaccine Weekly, August 17th, 2005
According to a study from the United States, "MTB41 is a mycobacterium antigen that is recognized by CD4+ T cells early after experimental infection of mice with Mycobacterium tuberculosis and by PBMC from healthy PPD-positive individuals. Immunization of mice with plasmid DNA encoding the MTB41 gene sequence results in the development of antigen-specific CD4+ and CD8+ T cells, and protection against challenge with virulent M. tuberculosis."
"In the present studies, in contrast to DNA...
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