Vaccine Development

Method to rapidly assess antigen-specific T-cell response developed

Published in Vaccine Weekly, August 24th, 2005

Scientists have developed a method for the rapid assessment of recognition efficiency and functional capacity of antigen-specific T-cell responses.

According to recent research from the United States, "It is increasingly recognized that cells within an antigen-specific CD8 T-cell population may be diverse in recognition efficiency for target, which may significantly affect the overall efficacy of the response in clinical settings such as viral infections and cancer. CD8 T cells with seemingly identical antigen specificity, particularly those elicited by cancer vaccines, may be heterogeneous for sensitivity and recognition efficiency for the cognate peptide and...

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Source: Vaccine Weekly (2005-08-24)

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