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HIV/AIDS Vaccines

Researchers detail new studies and findings in the area of HIV/AIDS vaccines

Published in Vaccine Weekly, August 24th, 2005

HIV/AIDS vaccines data are the focus of recent research from the United States and People's Republic of China.

Study 1: Immunization with a multiclade envelope HIV vaccine candidate expands the extent of virus neutralization.

"Although the V3 loop of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) effectively elicits potent neutralizing antibody responses, the specificity of the antibody response is often restricted to T cell line adapted (TCLA) strains and a small subset of primary isolates, limiting its utility for an AIDS vaccine. In this study, we have compared Env immunogens with substituted V3 regions to combinations of strains...

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