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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . August 31st, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Cancer Vaccine - Electrofusion process can increase immunogenicity of human cells

Ebola Vaccine - Live vaccine protects primates against Ebola and Marburg viruses

Herpes Vaccine - Plasmid-encoded IL-15 protects against herpes virus

Neurocysticercosis Vaccine - Vaccination of pigs controls human neurocysticercosis

Tuberculosis Vaccine - Multicomponent antituberculous vaccine developed

Adenovirus Vector - Capsid modifications enable flexible targeting of adenovirus vectors

Adverse Drug Reaction - Epidemiology study reports new info on hypersensitivity reactions to Abacavir

Adverse Drug Reaction - Serious adverse events associated with BCG vaccine still occurring in Canada

Allergy Medicine - Oral tolerance in absence of naturally occurring Tregs examined

Anthrax - Method to detect Bacillus anthracis protective antigen developed

Anthrax Vaccines - Reports advance knowledge in anthrax vaccines research

Cancer Vaccines - New findings in the area of cancer vaccines detailed

Antitumor Agents - Potential new antitumor agents derived from camphorato

Apoptosis - Pancratistatin targeted mitochondria specific to cancer cells for apoptosis

Asthma Vaccine - DNA vaccines for treatment of allergic disorders reviewed

Avian Adenovirus - Deletion of open reading frames from avian adenovirus examined

Avian Influenza - 5N1 Avian Influenza Vaccine program in final stages of preclinical development

Awards - Society honors five scientists for outstanding work in blood cancer research

Cancer Vaccines - New research in the area of cancer vaccines detailed

Borna Disease Vaccine - Borna disease virus proteins needed for BDV-like particles identified

Brucellosis Vaccine - Immune responses in water buffalo after Brucella vaccine evaluated

Cancer Vaccine - Phase I study of TNF-alpha AutoVaccIne for metastatic cancer conducted

Cancer Vaccines - New findings in the area of cancer vaccines described

Cancer Vaccines - Researchers detail new studies and findings in the area of cancer vaccines

Candidiasis Vaccine -  C. albicans epitope protects against systemic candidiasis

Cancer Vaccines - Researchers' data advance cancer vaccines research

Chickenpox Vaccine - Retinitis reported after varicella vaccination in child with leukemia

Chickenpox Vaccine - U.S. varicella vaccine shortage and doctor practices examined

Childhood Immunization - Children rarely receive vaccinations as recommended

Childhood Immunization - No link between multiple vaccinations, hospitalization for nontargeted diseases

Collaborations - Companies collaborate on DNA vaccine technology

Colon Cancer - Melatonin potentiated flavone-induced apoptosis in human colon cancer cells

Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge

Cysticercosis Vaccine - Synthetic peptide-based vaccine controls cysticercosis in pigs

DNA Vaccine -  Lactococcus lactis can deliver DNA into mammalian epithelial cells

DNA Vaccine - Beta-amino ester polymers facilitate in vivo DNA transfection

DNA Vaccine - Repressor protein immobilized for binding of plasmid DNA

Dendritic Cell Vaccine - Antigen presentation by dendritic and B cells optimize immunity

Dendritic Cell Vaccine - HLA-DO transduced in dendritic cells modulates MHC antigen processing

Diabetes Therapy - Researchers provide details of new studies and findings in the area of diabetes therapy

HIV/AIDS Vaccines - Recent findings in HIV/AIDS vaccines provide new insights

Drug Development - New class of vaccines include killed but metabolically active microbes

Drug Resistance - Anticancer multidrug resistance mediated by MRP1

Encephalomyelitis Vaccine - Co-infection with Trypanosoma brucei prevents encephalomyelitis

Etoposide - Topotecan and etoposide phosphate treated recurrent ovarian cancer

Finance - DNA-focused biopharmaceutical company reports Q2 2005 financial results

Finance - Genetics-focused drug development company reports Q2 2005 financial results

Leishmaniasis Vaccines - Studies advance knowledge in leishmaniasis vaccines research

Finance - Immunotherapies company reports Q2 revenue of $1 million

Finance - Vaccine maker reports second-quarter 2005 financial results

Grants - Harvard and Crucell receive $19.2 million NIH grant to develop AdVac vaccines

HIV/AIDS Prevention - Survey uncovers surprising attitudes toward HIV vaccine research

HIV/AIDS Research - Research shows random fluctuations in gene expression impacts HIV cells

HIV/AIDS Research - Tests demonstrated betulinol derivative inhibits HIV-1 replication

Tuberculosis Vaccines - Researchers' work adds to tuberculosis vaccines body of knowledge

HIV/AIDS Treatment - Secretary Leavitt urged to have PAHO examine HIV/AIDS treatment

HIV/AIDS Vaccine - Efficacy of SHIV 89.6 proviral DNA vaccine against SIVmac239 examined

HIV/AIDS Vaccine - HIV-peptide vaccine reduces viral burden in high-responder patients

HIV/AIDS Vaccine - Lentiviral siRNAs targeting conserved HIV RNA sequences developed

HIV/AIDS Vaccines - New findings in the area of HIV/AIDS vaccines described

Vaccines Adjuvant - New findings in the area of vaccines adjuvant detailed

Haemophilus Vaccines - Recent findings illuminate research in haemophilus vaccines

Heart Disease Therapy - Long-term cardiac gene expression achieved using coxsackieviral vector

Hepatitis A Prevention - Toddler immunization programs reduce the incidence of hepatitis A in Israel

Hepatitis A Vaccine - Rates of hepatitis A drop in U.S. after vaccine implementation

Hepatitis B Treatment - Therapy for chronic hepatitis B achieves primary endpoint in phase 3 trial

Hepatitis C Treatment - Patient enrolment begun in phase 1/2 clinical trial on hepatitis C therapy

Vaccines Adjuvant - Recent findings in vaccines adjuvant provide new insights

Human Papillomavirus - One amino acid substitution improves immunogenicity of HPV16 epitope

Human Papillomavirus Vaccines - Reports describe recent advances in human papillomavirus vaccines research

Imidazole - Development and exploitation of CK2 inhibitors discussed

Immunology - Recent findings in immunology described

Infectious Disease Risk Factors - Human & animal infection by microbes of high pathogenic potential examined

Influenza - VIB signs cooperation agreement for the development of a new flu vaccine

Influenza - Web resource details value of dose-sparing injection devices

Influenza Vaccine - Biotech company receives flu vaccine production license from Chinese state FDA

Influenza Vaccine - Company awarded NIH grant for flu-vaccine development

Influenza Vaccine - Exercise-enhanced influenza immunity mediated by psychosocial factors

Influenza Vaccine - Influenza vaccination affects markers of inflammation and lipid profile

Influenza Vaccines - Research in influenza vaccines provides new insights

Kidney Disease - Pharmaceutical company expands access to kidney disease treatment

Kinase Inhibitors - Cutaneous side effects of kinase inhibitors and blocking antibodies studied

Leishmaniasis Vaccine - Leishmania vaccine causes nitric oxide-mediated amastigote apoptosis

Leishmaniasis Vaccines - Researchers describe findings in leishmaniasis vaccines studies

Leukemia Vaccines - Research add new data to leukemia vaccines body of knowledge

Liposomes - Transferrin modification of liposomes assessed

Liver Cancer Vaccine - Dendritic cell vaccine plus IL-12 shows promise against liver cancer

Lung Cancer - Emodin induced apoptosis in human lung adenocarcinoma cells

MMR Vaccines - Recent findings in MMR vaccines described

Malaria Vaccine - Antibodies induced by polypeptides linked to P. vivax immunity

Malaria Vaccine - Genetic diversity of Plasmodium vivax merozoite protein gene reported

Malaria Vaccine - Glycosylphosphatidylinositol influence on malaria vaccines explored

Marketing - International pharmaceutical group supports DTC advertising guiding principles

Melanoma Vaccine - Active antigen-specific immunotherapy of melanoma reviewed

Melanoma Vaccine - Cytokine secretion by CD4+T cells reported after dendritic cell vaccine

Melanoma Vaccine - Heat shock/MAGE-3 fusion protein vaccine enhances immunity to MAGE-3

Meningitis - Killer Hib virtually wiped out in Africa

Meningitis Vaccine - Meningococcal conjugate vaccine efficacy decreases with time

Meningitis Vaccine - Porin A-specific antibody avidity after meningococcal disease reported

Meningococcal Vaccine - Antigens that protect against meningococcal infection identified

Mumps Vaccine - Effectiveness of mumps component of MMR vaccine investigated

Myeloma - Atiprimod induced apoptosis in multiple myeloma cells

Nosocomial Infection - Risk of infection in institutions for elderly people examined

Onchocerciasis Vaccine -  Onchocerca volvulus dehydrogenase characterized

Ovarian Cancer - Cytotoxicity of combinatory taxane and platinum treatment evaluated

Ovarian Cancer - Safety and efficacy of TLK286 assessed

Parkinson Disease - Sonic hedgehog delivered by virus protects neurons against toxicity

Patents - Gene-focused company announces patent issuance to make adeno-associated virus

Personnel - Biotechnology company announces appointment of medical director

Personnel - Nanotechnology company names Indevus CEO Michael W. Rogers nonexecutive director

Personnel - Three researchers named departmental chairs by children's research hospital

Pertussis - Recent rise in whooping cough among teens great concern for school nurses

Pertussis Vaccine - Shifts of Bordetella pertussis variants in Sweden reported

Philanthropy - Philanthropist announced partnership to provide food to HIV/AIDS patients

Plague Vaccine -  Yersinia pestis Yop secretion protein F protects against plague

Pneumococcal Vaccines - Studies add new findings to pneumococcal vaccines body of knowledge

Pneumonia - Immunity to Klebsiella pneumoniae infection examined

Poxviruses - Interleukin-4-expressing poxviruses reviewed

Prostate Cancer Vaccines - New findings in prostate cancer vaccines described

Protein Production - Baculovirus expression optimized for protein production in insect cells

Protein Production - Production of biologically active GM-CSF in sugarcane reported

Rabies Epidemiology - Rabies in Lublin voivodeship in 1999-2004 reported

Rabies Vaccine - Rabies human diploid cell vaccine protects against bat lyssaviruses

Renal Disease - Hepatitis B vaccine doses trigger seroconversion in predialysis patients

SARS Vaccine - Antibody responses to individual proteins of SARS coronavirus reported

Salmonella Vaccines - Findings describe new data in salmonella vaccines research

Salmonellosis Vaccine -  Salmonella vaccine carrier clearance prevents enhanced T cell response

Schistosomiasis Vaccine - Vaccine candidate from Schistosoma japonicum characterized

Smallpox Vaccine - Reactions to smallpox vaccination outlined

Smallpox Vaccine - Viral IL-1beta receptor inactivation improves CD8+ memory responses

Smallpox Vaccines - New findings in smallpox vaccines described

Toxoplasmosis Vaccines - Researchers report details of new studies and findings in the area of toxoplasmosis vaccines

Tuberculosis - Collaboration announced to develop rapid diagnostic test for tuberculosis

Tuberculosis - Findings advance knowledge in tuberculosis research

Tuberculosis Vaccine - DNA vaccine in microspheres enhances protection against tuberculosis

Tuberculosis Vaccine - Plasmid DNA vaccination reviewed

Tuberculosis Vaccine - Prime-boost immunization strategies for tuberculosis reviewed

Tuberculosis Vaccines - Research add new data to tuberculosis vaccines body of knowledge

Tularemia Vaccines - Reports describe recent advances in tularemia vaccines research

Vaccine Development - Animal models used to guide rational vaccine design

Vaccine Efficacy - Dendritic cell vaccine accelerates CD8+ memory and prime-boost response

Vaccine Efficacy - Life events and antibody status effects on vaccination examined

Vaccine Vector - Lentiviral vectors appear safe and effective for fetal gene delivery

Vaccine Vector - Transgene expression prolonged in salivary glands after transduction

Vaccines Adjuvant - Findings in vaccines adjuvant provide new insights

Vector Development - Conserved regions of tyrosine hydroxylase promoter characterized

Vector Development - New data illuminates research in vector development

West Nile Virus - Milestone in development of test for West Nile virus infection achieved

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