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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . September 7th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Cancer Vaccine - Carbohydrate vaccines as immunotherapy for cancer reviewed

Colon Cancer Vaccine - Oral vaccine induces immune responses against carcinoembryonic antigen

Lassa Fever Vaccine - New vaccine for prevention of Lassa fever developed

Prostate Cancer Vaccine - Antibody to prostate-specific membrane antigen used for cancer therapy

Vaccine Vector - Interference with IL-1-signaling reduces toxicity of adenovirus vectors

Adolescent Health - Challenges to vaccinating adolescents outlined

Allergy & Immunology - MDP1 appears to be potential adjuvant for CpG DNA-based immune therapies

Allergy Medicine - Dendritic cell vaccine does not protect against allergen responses

Antiproliferative Activity - Lamprey gonadotropin-releasing hormone III inhibited breast cancer cell growth

Apoptosis - Apoptosis induced in prostate cancer cells by pachymic acid from Poria cocos

Apoptosis - Novel polysaccharide induced apoptosis in HL-60 cells

Cancer Vaccines - New findings in cancer vaccines described

Astrocytomas - Novel platinum(IV) compound with anticancer properties discussed

Breast Cancer - CD44 attenuated metastatic invasion during breast cancer progression

Breast Cancer Vaccine - Expression of SIVA-1 protein enhances apoptosis in breast cancer cells

Camptothecin - Chemotherapy scheduling altered effect of histone deacetylase inhibitors

Cancer Prevention - Non-steroidal anti-inflammatory drugs used for prevention of cancer

Cancer Therapy - Cepharanthine enhanced sensitivity of anticancer agents in K562 cells

Cancer Vaccines - Research in cancer vaccines provides new insights

Cancer Vaccine - Co-stimulation of antigen-presenting cells induced high avidity CTLs

Cancer Vaccine - Cytotoxic t cell targeting sensitizes malignant glioma to chemotherapy

Cancer Vaccine - Function of tumor-specific T lymphocytes more important than numbers

Cancer Vaccine - Method developed to screen for potential antigens for cancer vaccines

Cancer Vaccine - Method to target B lymphoma cells to antigen-presenting cells developed

Cancer Vaccine - Novel CTL epitopes derived from two cancer germline genes identified

Cancer Vaccines - Researchers report details of new studies and findings in the area of cancer vaccines

Cancer Vaccine - Peptide disables mitochondrial function in HER-2-positive cancer cells

Cancer Vaccine - Phase 1 study of TNF-alpha AutoVaccIne in metastatic cancer reported

Cancer Vaccine - Promising therapeutic approaches to vaccination for cancer reviewed

Cancer Vaccine - Tumor antigen-specific T helper cells in cancer immunotherapy reviewed

Cancer Vaccine - Tumor-associated carbohydrate antigens are avenue for cancer prevention

Cancer Vaccine - Tumor-reactive CD8+ T cells confer superior antitumor immunity

Cancer Vaccines - Studies describe new findings in cancer vaccines research

Cancer Vaccine - Vaccine induces autoantibodies to prostate-specific membrane antigen

Cancer Vaccines - Findings in cancer vaccines provide new insights

DPT Vaccines - Reports advance knowledge in DPT vaccines research

Cardiovascular Disease - DNA vaccine with receptor coding plasmids impair cardiac function

Cisplatin - Novel platinum (IV) complexes induced rapid tumor cell death in vitro

Cytomegalovirus Vaccines - Studies advance knowledge in cytomegalovirus vaccines research

DNA Vaccine - Cross-linked small polyethylenimines deliver DNA efficiently to cells

DNA Vaccine - Naked DNA encoding MCP-1 and RANTES protects against renal injury

HIV/AIDS Vaccines - Recent findings in HIV/AIDS vaccines described

DPT Vaccines - Findings advance knowledge in DPT vaccines research

Dengue Fever - Dengue virus replication analyzed, nitric oxide-mediated suppression shown

Diabetes Vaccine - CpG ODN have limited effect in preventing type 1 diabetes in NOD mice

Drug Development - GMP materials pass QC release for phase I/II trial in cervical cancer

Drug Development - Phase I trial initiated for Venezuelan equine encephalitis vaccine candidate

Malaria Vaccines - Researchers report details of new studies and findings in the area of malaria vaccines

Encephalitis - Phase 3 clinical trials for Japanese encephalitis vaccine approved in Europe

Finance - Company focused on transdermal science reports Q2 2005 results, business update

Finance - Pharma company announces financial results

Finance - Vaccine maker reports second quarter revenue of $1.2 million

Gastric Cancer - Cytotoxic effects of pemetrexed in gastric cancer cells discussed

Gastroenteritis - Oral vaccine from bacterial ghosts may protect against E. coli

Vaccines Vector - Researchers publish new studies and findings in the area of vaccines vector

Glioblastoma Vaccine - Dendritic cell vaccine in glioblastoma induces T-cell responses

Green Tea - Proteasome-inhibitory and apoptosis-inducing potencies of (-)-EGCG examined

HIV/AIDS Vaccine - Mucosal alloimmunization inhibits SIV infectivity

HIV/AIDS Vaccines - New findings in the area of HIV/AIDS vaccines detailed

Helicobacter Pylori - Antibody role in colonization and infection by H. pylori reviewed

Hemophilia - Data for Advate confirm safety and efficacy in hemophilia A patients

Hepatitis B Vaccine - HBV vaccine questionable in patients receiving lamividine post liver transplant

Hepatitis Pathogenesis - Hepatitis B virus X protein up-regulates lymphotoxin-alpha expression

Herpes Vaccine - Adjuvants for DNA vaccine against herpes simplex virus compared

Human Papillomavirus - HPV escapes recognition through phosphoinositide 3-kinase activation

Immunization -  Anaplasma MSP2-specific T cells disappear rapidly after challenge

Immunology - NK-dependent DC maturation mediated by TNF-alpha and IFN-gamma

Influenza - Online educational materials promote pediatric influenza vaccination

Influenza - Pharmaceutical company receives grant to test influenza drug candidate

Influenza - Surveillance, targeted use of antivirals, could help prevent flu pandemic

Influenza Vaccine - Respiratory vaccination of mice against influenza virus examined

Influenza Vaccines - Researchers detail new studies and findings in the area of influenza vaccines

Leishmaniasis Vaccine - DNA vaccine protects against Leishmania donovani

Leishmaniasis Vaccines - Reports advance knowledge in leishmaniasis vaccines research

Leukemia Vaccine - Epitopes of receptor for hyaluronic acid-mediated motility identified

Lung Cancer - Aspirin inhibited NF-kappaB activation in lung epithelial cell line

Malaria Vaccine - Researchers peg five peptides as candidates in designing a malaria vaccine

Malaria Vaccines - Recent studies add new data to malaria vaccines research

Measles Vaccine - Window of vulnerability to measles in infants in rural Mali determined

Melanoma Vaccine - Fusion with IL-2 enhances immunogenicity of anti-idiotypic antibody

Melanoma Vaccine - Noncanonical melanoma-associated T cell epitopes identified

Melanoma Vaccine - Vaccine targets tumor microenvironment for treatment of melanoma

Melanoma Vaccines - Data advance knowledge in melanoma vaccines research

Mergers & Acquisitions - Stockholders approve business combination with IDM

Muscular Dystrophy - Researchers' findings advance muscular dystrophy research

Mycobacterium Vaccine - Cytokine gene expression profiles of dendritic cells described

Pancreatic Cancer - Biopharma company reports second quarter 2005 financial results

Pancreatic Cancer - Vascular endothelial growth factor receptor promotes tumor invasion

Patents - Biotechnology company announces issuance of its first Canadian patent

Pediatric Sarcoma - Vincristine, ifosfamide, and doxorubicin treated pediatric sarcomas

Pertussis Vaccine - Acellular pertussis vaccines safe and effective in adolescents

Pertussis Vaccine - Clinical and economic effects of pertussis outbreaks reviewed

Pertussis Vaccines - Recent findings illuminate research in pertussis vaccines

Pneumococcal Disease - Chronic illness increases incidence of pneumococcal disease in adults

Pneumococcal Vaccines - Findings advance knowledge in pneumococcal vaccines research

Polio Vaccine - Genomic analysis of vaccine-derived poliovirus strains conducted

Proanthocyanidin - Proanthocyanidin from grape seeds enhanced anti-tumor effect of doxorubicin

Prostate Cancer - New class of inhibitors prevented invasion of prostate cancer cells

Respiratory Syncytial Virus - RSV immunopathology studied, innate interferon role defined

Tuberculosis Prevention - Boosting the BCG vaccine to beat tuberculosis

Tuberculosis Vaccine - Role of TNF-alpha in pulmonary tuberculosis in guinea pig examined

Tuberculosis Vaccines - Researchers' data advance tuberculosis vaccines research

Tumor Suppressor - Unique complex between bacterial azurin and tumor-suppressor protein p53 studied

Vaccine Adjuvant - Leptin promotes differentiation and survival of human dendritic cells

Vaccine Adjuvant - Vitamin E TPGS enhances immune response to nasal diphtheria vaccine

Vaccine Delivery - DNA released from dendriplexes encapsulated in PGLA nanoparticles

Vaccine Delivery - Decision-making at surface of intact or barrier-disrupted skin examined

Vaccines Vector - Researchers detail new studies and findings in the area of vaccines vector

Varicella - Hospitalizations because of chicken pox down dramatically

Whooping Cough - Survey reveals school nurses concerned about surge in whopping cough in teens

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