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Vaccine Weekly

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Antiproliferative Activity



Hopane and oleanane glycosides exhibited antiproliferative activity



September 14th, 2005

Scientists claimed hopane and oleanane glycosides exhibited antiproliferative activity.

According to a study from Egypt, "Three new hopane saponins, lotoidosides A-C (1-3), and four new oleanane saponins, lotoidosides D-G (4-7), were isolated from the roots of Glinus lotoides L. (Molluginaceae)."

"Their structures were determined by extensive 1D- and 2D-NMR spectroscopy and ESI-MS analysis. The antiproliferative activity of compounds 1-7 was evaluated using three continuous murine and human culture cell lines J774.A1, HEK-293, WEHI-164," explained A.I. Hamed and colleagues, Aswan Faculty of Science.

The researchers...


Source: Vaccine Weekly (2005-09-14)

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