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Vaccine Weekly

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Cancer Vaccines



Recent findings in cancer vaccines provide new insights



September 14th, 2005

Cancer vaccines research advances have been reported from Germany and France.

Study 1: Chemosensitization of pancreatic carcinoma cells enhanced T cell-mediated cytotoxicity induced by tumor lysate-pulsed dendritic cells.

"Dendritic cells (DCs) can induce cytotoxic T-cell (CTL) responses against tumor antigens in vitro and in vivo, yet few cancer patients experience tumor regression after DC-based vaccination. Combination with other treatment modalities, such as radiation or pharmacologic anticancer agents, may reduce tumor cell resistance against immune responses," researchers in Germany report.

"The authors tested whether...


Source: Vaccine Weekly (2005-09-14)

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