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Apoptosis
Panduratin A induced apoptosis
September 14th, 2005
Panduratin A was proposed as an anti-inflammatory agent. According to recent research from Korea, "We previously showed that panduratin A isolated from an extract of Kaempferia pandurata (Zingiberaceae) was a strong inhibitor of cyclooxygenase-2 (COX-2) in RAW264.7 cells, suggesting a potential use of panduratin A as an anti-inflammatory agent. In the present study, we have investigated the effects of panduratin A on cytoplasmic levels of COX-2, as well as proliferation and apoptosis in human colon cancer cells HT-29." "Cell proliferation and induction of apoptosis was determined by the MTT assay, DNA fragmentation measurement, flow cytometric...
Source: Vaccine Weekly (2005-09-14)
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