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Allergy & Immunology
New allergen exposure may act as adjuvant to initial allergen
September 14th, 2005
New allergen exposure may exert an adjuvant effect on the first allergen used in the sensitization. "Oral tolerance is an important approach in allergic diseases and murine model can provide useful information to improve its understanding and therapeutic measures. This study was conducted to address the influence of non-related allergen sensitization in immunized mice with the mite Blomia tropicalis (Bt) or ovalbumin (OVA) or with both Bt/OVA allergens. Furthermore, we sought to verify oral tolerance effect in the Bt/OVA co-immunization model," researchers in Brazil report. "Mice sensitized with Bt and then exposed to OVA developed an enhanced...
Source: Vaccine Weekly (2005-09-14)
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