Breast Cancer Vaccine Development
Dendritic cell vaccine stimulates mammaglobin-specific T cells
Published in Vaccine Weekly, September 28th, 2005
According to recent research published in the journal Breast Cancer Research And Treatment, "Proteins can be efficiently introduced into cells when fused to a protein transduction domain, such as Tat from the human immunodeficiency virus. We recently reported that dendritic cells transduced with a Tat fusion protein containing the extracellular domain of Her2/neu (Tat-Her2/neu) induced CD8 cytotoxic T lymphocytes (CTL) that specifically lysed Her2/neu-expressing breast and ovarian cancer cells."
"In the current study we further...
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Source: Vaccine Weekly (2005-09-28)
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