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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . October 5th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Avian Influenza - Methods to contain pandemic influenza at the source examined

Melanoma Vaccine Development - Protection against melanoma found without autoimmune depigmentation

Tuberculosis Vaccine Development - Variant tricarboxylic acid cycle found in M. tuberculosis

Vaccine Adjuvant - Role of adjuvants in development of mucosal vaccines reviewed

Vaccine Efficacy - QPCR used to assign infectious potencies to adenovirus-based vaccines

Addiction Medicine - Drug users in Ireland remain vulnerable to bloodborne pathogens

Allergy & Immunology - Natural killer cells modulate immune response after hepatitis B vaccination

Allergy Medicine - DNA vaccine inhibits inflammation in mice sensitized with allergen

Anthrax Vaccine Development - Edible crop transformed with pagA gene of Bacillus anthracis

Anthrax Vaccines - New data illuminates research in anthrax vaccines

Apoptosis - Syndecan-2 overexpression induced osteosarcoma cell apoptosis

Influenza Vaccines - Recent findings in influenza vaccines described

Arthritis Vaccine Development - IL-1 beta peptides designed by molecular modeling improve arthritis

Asthma Therapy - Microbes and products have potential in management of allergic asthma

Bacterial Meningitis - Risk factors for pneumococcal meningitis in France outlined

Brain Cancer Vaccine Development - Intracranial tumors treated with dendritic cell-tumor cell vaccines

Breast Cancer Vaccines - Researchers' findings advance breast cancer vaccines research

Malaria Vaccines - Researchers detail new studies and findings in the area of malaria vaccines

Business Update - GlaxoSmithKline acquires Pennsylvania vaccine manufacturing facility

Cancer Therapy - Arsenic trioxide inhibited invasion of HT1080 human fibrosarcoma cells

Cancer Therapy - Histone deacetylase inhibitors showed antitumor effects on Ewing family tumors

Cancer Therapy - Oxaliplatin used to treat recurrent or refractory non-Hodgkin lymphoma

Cancer Therapy - Syntheses and biological activities of disaccharide daunorubicins examined

Cancer Vaccine Development - Antigen-specific CD4+ regulatory T cells in cancer reviewed

Melanoma Vaccines - Studies advance knowledge in melanoma vaccines research

Cancer Vaccine Development - Cell lines from tumors induced by TC-1 cells characterized

Cancer Vaccine Development - Mimotope peptide-based cancer vaccine selected by BAT antibody

Cancer Vaccine Development - Promising therapeutic approaches to cancer vaccines reviewed

Cancer Vaccines - Findings in cancer vaccines provide new insights

Chlamydia Vaccine Development - Clearance of Chlamydia pneumoniae infection in mice examined

Clinical Trials - Encouraging immune response seen in "Prime/Boost" phase I HIV vaccine study

Tuberculosis Vaccines - Research in tuberculosis vaccines provides new insights

Clinical Trials - Favorable clinical results reported for HIV vaccine

Clinical Trials - Potential nucleoside analogue drug for hepatitis B, HIV enters Phase 2 studies

Collaborations - Deal signed for vaccine candidate for group A streptococcal disease

DNA Research - A novel plasmid DNA purification process is reported

DNA Vaccine Development - Humoral and cytokine responses to Fasciola hepatica vaccine examined

DNA Vaccine Development - Reporter gene expression in dendritic cells investigated

Tuberculosis Vaccines - Researchers provide details of new studies and findings in the area of tuberculosis vaccines

Dendritic Cell Vaccine Development - Immunostimulatory properties of dendritic cells examined

Dendritic Cells - Phenotype and function of intestinal dendritic cells investigated

Dengue Fever - Dengue virus vaccine candidates evaluated in rhesus macaque model

Drug Research - Bioactivity of biflorin evaluated

Drug Resistance - Proton pump inhibitors reduced tumor resistance

Epidemiology - Origin of SIVmac and SIVstm unraveled

Finance - Venture fund company makes seed investment in Azidex Pharmaceuticals

Gastric Cancer - Gastric cancer sensitivity to 5-FU/CDDP evaluated

Gastric Cancer - Synergistic interaction between oxaliplatin and SN-38 examined

Gene Therapy - Local immunomodulation improves osteogenesis induced by gene therapy

Gingivitis Vaccine Development - DNA vaccine protects mice against Porphyromonas gingivalis

HIV/AIDS Vaccine Development - Antigen-presenting cells do not modulate immune responses

HIV/AIDS Vaccine Development - Glycosylation affected the efficacy of vaccine against SIV

HIV/AIDS Vaccine Development - HIV canarypox vaccine is safe and immunogenic in HIV-infected patients

HIV/AIDS Vaccine Development - Immunogenicity of HIV-1 envelope glycoprotein complex evaluated

HIV/AIDS Vaccine Development - Mucosal alloimmunization inhibits SIV infectivity

HIV/AIDS Vaccine Development - Properties of peptide mimotopes of HIV carbohydrate antigens reported

HIV/AIDS Vaccine Development - Replicating adenovirus-HIV vaccines are better at eliciting immunity

HIV/AIDS Vaccine Development - Vaccine effect on HIV-1 viremia after antiretroviral therapy reported

HIV/AIDS Vaccine Development - Virions with HIV Env induce high-titer neutralizing antibody responses

HIV/AIDS Vaccines - Researchers' findings advance HIV/AIDS vaccines research

Haemophilus Vaccine Development - Epiglottitis incidence reduced after Haemophilus influenzae vaccine

Haemophilus Vaccine Development - Hib vaccine failure linked to multiple copies of capsulation b locus

Health Prevention - Rumor of shortage of condoms in Uganda is untrue

Helicobacter Vaccine Development - Oral vaccine elicits response against Helicobacter pylori

Hepatitis C Virus - Alternate priming approaches enhance hepatitis C vaccine in rhesus macaques

Hurricane Relief - Central Florida hospital group offers free health exams to hurricane evacuees

Immunology - Immune response to tuberculin protein in GATA-3-transgenic mice studied

Influenza - Agency approves new influenza vaccine for upcoming flu season

Influenza - GlaxoSmithKline announces U.S. FDA approval of Fluarix

Influenza - U.S. government buys vaccine, antivirals for potential influenza pandemic

Influenza Epidemiology - Need for effective influenza vaccine in infants demonstrated

Influenza Vaccine Development - Method for nasal influenza vaccine delivery using chitosan developed

Influenza Vaccine Development - Neuraminidase-expressing DNAs protect against influenza virus infection

Influenza Vaccine Development - Respiratory vaccination of mice against influenza virus examined

Influenza Vaccine Efficacy - Influenza vaccines are safe and effficacious in HIV-positive patients

Influenza Vaccines - New findings in the area of influenza vaccines detailed

Islet Transplantation - Viral immune regulation in pancreatic islet transplantation examined

Leishmaniasis Vaccine Development - T helper cell type in leishmaniasis vaccine discovery examined

Leukemia Vaccine Development - Receptor epitopes recognized by T cells of leukemia patients identified

Liposome Vaccine Development - PRA International helps complete BLP25 liposome vaccine phase III study

Lung Cancer - Paper addresses new vector system in treatment of models of lung cancer

Malaria - Recent findings in malaria described

Malaria Vaccine Development - Full-length cDNA libraries used to develop malaria vaccines

Malaria Vaccines - Research in malaria vaccines provides new insights

Melanoma - Data presented showing MDA-7/IL-24 controls growth of melanoma cells

Melanoma Vaccines - Researchers describe findings in melanoma vaccines studies

Meningitis Vaccine Development - Investigational meningitis vaccine immunogenic in children

Meningitis Vaccine Development - Meningococcal outer membrane vesicle vaccine elicited immune response

Meningococcal Vaccines - Research add new data to meningococcal vaccines body of knowledge

Mergers & Acquisitions - GlaxoSmithKline to acquire biotech company

Microencapsulation - Release of DNA from dendriplexes encapsulated in PLGA nanoparticles

Mucosal Immunization - Coated nanoparticles for new mucosal vaccine delivery system developed

Myasthenia Gravis Vaccine Development - Vaccines against myasthenia gravis reviewed

Oral Cancer - Flavonoid glycosides inhibited oral cancer cell proliferation

Pancreatic Cancer - Histone deacetylase inhibitors induced caspase-independent apoptosis

Pertussis Vaccine Development -  B. pertussis in countries with different vaccine policies analyzed

Pertussis Vaccines - New findings in the area of pertussis vaccines detailed

Pneumococcal Vaccine Development - Pneumococcal infections in population with low HIV prevalence examined

Polio Vaccines - Researchers detail new studies and findings in the area of polio vaccines

Porphyromonas Vaccine Development - Vaccine effect on P. gingivalis infection is adjuvant-dependent

Pseudomonas Vaccine Development - Immunization against Pseudomonas aeruginosa reviewed

Respiratory Syncytial Virus - G protein fragment and RSV epitope enhance immune responses

Rotavirus Vaccines - New findings in the area of rotavirus vaccines described

SARS Vaccine Development - Expression of SARS-CoV spike protein subunit elicits immune responses

Schistosomiasis Vaccine Development -  Schistosoma mansoni protein protects against schistosomiasis

Smallpox - LIAI scientists make major finding on potential smallpox treatment

Smallpox - Published study examines smallpox vaccine candidate LC16m8 in mice

Smallpox Vaccine Development - Vaccinia virus tropism determined by expression of virus receptor

Tetanus Vaccine Development - Promoters for antigen expression in Salmonella developed

Tick-Borne Disease -  Ixodes scapularis cDNAs protective against infestation characterized

Tick-Borne Disease - Cross-reactive tick cement antigen used for broad-spectrum tick vaccine

Tick-Borne Disease - Methods for preparation of tick-derived stabilates compared

Transplant Medicine - Hepatitis B core antibody positive donors increase lung transplant options

Transplantation Medicine - Complement proteins with mammalian vector enhances cell protection

Transplantation Medicine - Heterogeneous alterations in alloimmunity linked to immunization

Tuberculosis Vaccine Development - Proteomics identify membrane-associated proteins of M. tuberculosis

Tuberculosis Vaccines - Recent findings in tuberculosis vaccines provide new insights

Vaccine Delivery - DNA vaccination strategy defined by monitoring of antigen expression

Vaccine Delivery - Ex vivo transduction of dermal tissue for protein delivery described

Vaccine Delivery - Lipid vesicles used to deliver bacterial protein antigen

Vaccine Development - Procedure for large-scale preparation of plasmid DNA developed

Vaccine Development - U.S. FDA approves Proquad, a one-shot MMR and chickenpox vaccine

Vaccine Efficacy - Household cost-benefits of sustainable childhood immunization examined

Vaccine Efficacy - Low T-cell proliferation and high viral load limit vaccine efficacy

Vaccine Safety - Criticism of vaccines on World Wide Web reviewed

Vaccine Vector - Influenza A virus vector expressing active IL-2 generated

Vaccine Vector - Virus RNA replicons elicit distinct humoral immunity

Vaccines Vector - Researchers' work adds to vaccines vector body of knowledge

Vector Development - Findings describe new data in vector development research

Virology - Cytomegalovirus gene products block herpes-induced host protein shutoff

Virology - Foamy virus Bet proteins inhibit innate antiretroviral defense factors

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