Vaccine Delivery
Ex vivo transduction of dermal tissue for protein delivery described
Published in Vaccine Weekly, October 5th, 2005
According to a study from Israel, "Systemic delivery of therapeutic proteins through gene transfer approaches has been carried out mostly by ex vivo transduction of single cells or by direct in vivo injection of an expression vector. In this work an intact miniature biopsy of human dermis (microdermis) is harvested and transduced ex vivo by a viral vector encoding a gene for the therapeutic protein."
"The microdermis preserves its three-dimensional...
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Source: Vaccine Weekly (2005-10-05)
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