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Rotavirus Vaccine

Incidence of intussusception resulting from RotaShield estimated

Published in Vaccine Weekly, October 12th, 2005

Scientists estimate the incidence of intussusception resulting from RotaShield rotavirus vaccine in a recent issue of the Journal of Infectious Diseases.

According to a study from the United States, "RotaShield, a vaccine intended to prevent severe rotavirus diarrhea, was withdrawn in July 1999, nine months after it became available in the United States, because of a temporal association with intussusception events that occurred in vaccinated infants. We explore here the effect of age on the risk of intussusception. We reanalyzed a case-control database of the Centers for Disease Control and Prevention by use of a 21-day window, to define vaccine-associated...

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